Binary Classifier Calibration using an Ensemble of Near Isotonic Regression Models. [PDF]
Learning accurate probabilistic models from data is crucial in many practical tasks in data mining. In this paper we present a new non-parametric calibration method called \textit{ensemble of near isotonic regression} (ENIR). The method can be considered
Naeini MP, Cooper GF.
europepmc +2 more sources
Identifying change points in a covariate effect on time-to-event analysis with reduced isotonic regression. [PDF]
Isotonic regression is a useful tool to investigate the relationship between a quantitative covariate and a time-to-event outcome. The resulting non-parametric model is a monotonic step function of a covariate X and the steps can be viewed as change ...
Yong Ma, Yinglei Lai, John M Lachin
doaj +2 more sources
COMBINING ISOTONIC REGRESSION AND EM ALGORITHM TO PREDICT GENETIC RISK UNDER MONOTONICITY CONSTRAINT. [PDF]
In certain genetic studies, clinicians and genetic counselors are interested in estimating the cumulative risk of a disease for individuals with and without a rare deleterious mutation.
Qin J +5 more
europepmc +5 more sources
Relaxivity of Gadobutrol and Gadoteric Acid in Cerebrospinal Fluid at 3T. [PDF]
ABSTRACT Purpose The aim was to estimate T1 relaxivity of gadobutrol and gadoteric acid in cerebrospinal fluid (CSF) at 3T, to support research on CSF‐flow and the glymphatic system in humans utilizing T1 mapping after intrathecal injection. Methods Using a phantom, relaxivity was estimated for gadobutrol and gadoteric acid in lumbar CSF and an ...
Behndig S +5 more
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Exercise with fasting or isotonic drink? A randomized controlled trial in youth elite basketball players [PDF]
Background Pre-exercise carbohydrate intake is known to influence performance; however, data describing their effect on cardiorespiratory parameters is scarce.
Petra Márton +12 more
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A lightweight deep learning framework for reliable microscopy-based diagnosis of cutaneous leishmaniasis. [PDF]
Cutaneous leishmaniasis (CL) is a neglected tropical and zoonotic disease affecting both human and animal health, for which microscopic examination of Giemsa-stained slides remains the diagnostic reference standard despite being time-consuming and ...
Nisreen Osman E Ahmed +2 more
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A clinical prediction model for central venous catheter-associated bloodstream infections: derivation and validation from the MIMIC-IV cohort [PDF]
Background Central venous catheter-associated bloodstream infections (CVC–BSIs) significantly affect clinical outcomes in critically ill patients. Existing risk prediction models lack comprehensive integration of early clinical indicators.
Bo Song +3 more
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Dual active-set algorithm for optimal 3-monotone regression [PDF]
The paper considers a shape-constrained optimization problem of constructing monotone regression which has gained much attention over the recent years. This paper presents the results of constructing the nonlinear regression with $3$-monotone constraints.
Gudkov, Alexandr A. +2 more
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Determining the optimal ropivacaine concentration for spinal anaesthesia during day surgery for anorectal procedures: a dose-finding study [PDF]
Ropivacaine is a commonly utilized local anesthetic for spinal anesthesia (SA); however, its optimal concentration for elective anorectal surgery has not been thoroughly estimated.
Lu Chen +7 more
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Meta-analyses combine the estimators of individual means to estimate the common mean of a population. However, the common mean could be undefined or uninformative in some scenarios where individual means are “ordered” or “sparse”.
Nanami Taketomi +3 more
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