Results 31 to 40 of about 12,794 (158)

Isotonic quadriceps endurance is better associated with daily physical activity than quadriceps strength and power in COPD: an international multicentre cross-sectional trial

Scientific Reports, 2021
Knowledge about modifiable determinants of daily physical activity (PA) in patients with chronic obstructive pulmonary disease (COPD) is crucial to design effective PA interventions.
Erik Frykholm, Sarah Gephine, Didier Saey, Arthur Lemson, Peter Klijn, Eline bij de Vaate, François Maltais, Hieronymus van Hees, André Nyberg   +8 more
doaj   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

The reliability of Berger’s table in estimating 1-RM and 10-RM of the elbow flexor muscles in normal young adults

South African Journal of Physiotherapy, 2001
Isotonic strength training remains one of the methods of strengthening muscles, as it requires inexpensive materials. The method requires the determination of maximal isotonic strength or one repetition maximum [1-RM] and/or sub-maximal isotonic strength
A. O. Akinpelu, J. O. Iyaniwura, B. O. Ajagbe   +2 more
doaj   +1 more source

Fluorescent Hydrogel‐Based Strain Sensor With Machine Learning‐Augmented Performance

Advanced Intelligent Discovery, EarlyView.
Fluorescent hydrogel strain sensor based on carbon quantum dots enabling optical readout of deformation through strain‐dependent emission changes, coupled with Random Forest analysis to capture nonlinear fluorescence‐concentration relationships and identify optimal sensing conditions. Hydrogels are ideal matrices for bio‐integrated wearable sensors due
Tailai Chen, Tianlong Liu, Chao Lu, Rimsha Malik, Jin Zhang   +4 more
wiley   +1 more source

A Goodness-of-Fit Test for Log-Linearity in Cox Proportional Hazards Model Under Monotonic Covariate Effects

Mathematics
The Cox proportional hazards (PH) model is widely used because it models the covariates to the hazard through a log-linear effect. However, exploring flexible effects becomes desirable within the Cox PH framework when only a monotonic relationship ...
Huan Chen, Chuan-Fa Tang
doaj   +1 more source

How does the Kids SIPsmartER program impact the sugar‐sweetened beverage intake of students: An investigation beyond total treatment effect in randomized controlled trial

American Journal of Agricultural Economics, EarlyView.
Abstract This study develops and empirically estimates a structural framework to decompose the causal pathways of multilevel behavioral interventions targeting adolescent health behaviors. We apply this framework to the Kids SIPsmartER (KSS) program, a 6‐month, school‐based intervention evaluated through a clustered randomized controlled trial in rural
Naveen Abedin, Wen You, Annie Reid, Kathleen Porter, Brittany Kirkpatrick, Jamie Zoellner   +5 more
wiley   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen   +11 more
wiley   +1 more source

A Novel Non-Isotonic Statistical Bivariate Regression Method—Application to Stratigraphic Data Modeling and Interpolation

Mathematical and Computational Applications, 2020
The present paper deals with nonlinear, non-monotonic data regression. This paper introduces an efficient algorithm to perform data transformation from non-monotonic to monotonic to be paired with a statistical bivariate regression method.
Daniele Polucci, Michele Marchetti, Simone Fiori   +2 more
doaj   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

cgam: An R Package for the Constrained Generalized Additive Model

Journal of Statistical Software, 2019
The cgam package contains routines to fit the generalized additive model where the components may be modeled with shape and smoothness assumptions. The main routine is cgam and nineteen symbolic routines are provided to indicate the relationship between ...
Xiyue Liao, Mary C. Meyer
doaj   +1 more source