Results 51 to 60 of about 12,339 (203)

A Novel Non-Isotonic Statistical Bivariate Regression Method—Application to Stratigraphic Data Modeling and Interpolation

Mathematical and Computational Applications, 2020
The present paper deals with nonlinear, non-monotonic data regression. This paper introduces an efficient algorithm to perform data transformation from non-monotonic to monotonic to be paired with a statistical bivariate regression method.
Daniele Polucci, Michele Marchetti, Simone Fiori   +2 more
doaj   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen   +11 more
wiley   +1 more source

cgam: An R Package for the Constrained Generalized Additive Model

Journal of Statistical Software, 2019
The cgam package contains routines to fit the generalized additive model where the components may be modeled with shape and smoothness assumptions. The main routine is cgam and nineteen symbolic routines are provided to indicate the relationship between ...
Xiyue Liao, Mary C. Meyer
doaj   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

Sensitivity analysis in isotonic regression

Discrete Applied Mathematics, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

The Median Effective Analgesic Concentration of Ropivacaine in Sciatic Nerve Block Guided by Ultrasound After Arthroscopic Anterior Cruciate Ligament Reconstruction: A Double-Blind Up-Down Concentration-Finding Study

Frontiers in Medicine, 2022
BackgroundThe median effective analgesic concentration (MEAC; EC50 = effective concentration in 50% patients) of ropivacaine in sciatic nerve block guided by ultrasound (US) required for effective postoperative analgesia following arthroscopic anterior ...
Cheng Xu, Fei Gu, Chengyu Wang, Yang Liu, Rui Chen, Quanhong Zhou, Jie Lu   +6 more
doaj   +1 more source

Tailoring drug‐to‐lipid ratio in redox‐responsive lipid‐mimetic prodrug liposomes for superior cabazitaxel delivery and antitumor efficacy

BMEMat, EarlyView.
Redox‐responsive lipid‐mimetic prodrug liposomes with high drug‐to‐lipid ratios enhance cabazitaxel delivery, prolong circulation, and enable tumor‐selective drug release for superior antitumor efficacy and safety. Abstract Liposomes represent one of the most extensively investigated nanocarriers in drug delivery.
Shengyao Xu, Danping Wang, Si Zheng, Zhiyu Kuang, Ya Gao, Haiyu Zhao, Lurong Zhang, Jiayu Guo, Jingyi Zhang, Weiyao Li, Anhua Wang, Hongrui Lei, Zhonggui He, Ken‐ichiro Kamei, Jianzhao Niu, Lingyun Ma, Bingjun Sun   +16 more
wiley   +1 more source

Anti-Data Leakage Pipeline for Differentiated Thyroid Cancer Recurrence Prediction: Integrating SMOTE, Optuna-based Optimization, and Bootstrap BCa Validation

Journal of Applied Informatics and Computing
Thyroid cancer recurrence prediction remains a critical clinical challenge, as early identification of high-risk patients enables targeted monitoring and intervention.
Deri Rosadi, Sindhu Rakasiwi
doaj   +1 more source

The median effective analgesic concentration of ropivacaine in ultrasound-guided interscalene brachial plexus block after arthroscopic rotator cuff repair

Frontiers in Pharmacology, 2022
Background: The median effective analgesic concentration (MEAC) of ropivacaine in interscalene brachial plexus block (ISBPB) for postoperative analgesia after arthroscopic rotator cuff repair (ARCR) has not been determined. Therefore, this study aimed to
Cheng Xu, Fei Gu, Yang Liu, Rui Chen, Chengyu Wang, Jie Lu   +5 more
doaj   +1 more source

One‐Year Results of Accelerated Transepithelial Corneal Cross‐Linking for Progressive Keratoconus: A Prospective Interventional Study

Eye &ENT Research, EarlyView.
ABSTRACT Background Keratoconus is a progressive corneal ectatic disorder. Accelerated transepithelial corneal cross‐linking (ATE‐CXL) aims to halt progression while preserving the epithelium, but evidence on its 12‐month efficacy requires further evaluation.
Rafea Allawi Fayyadh, Omar Salim Mahmood, Aktham Badia Abdulelah, Husam Abu Dawood, Hashem Abu Serhan   +4 more
wiley   +1 more source