Results 1 to 10 of about 2,564 (175)

Efficacy and Safety of Remimazolam in Endoscopic Sedation—A Systematic Review and Meta-Analysis [PDF]

Frontiers in Medicine, 2021
Background: The aim of this systematic review and meta-analysis was to investigate the efficacy and safety of remimazolam in clinical endoscopic procedure sedation.Methods: The authors searched the databases of PubMed, Embase, and Cochrane Library for ...
Xianlin Zhu, Hongbai Wang, Yuan Jia
exaly   +4 more sources

Three cases of difficulty in achieving definitive loss of consciousness with remimazolam

JA Clinical Reports, 2022
Background Remimazolam is a novel, ultra-short-acting benzodiazepine used for general anesthesia. Because remimazolam is an emerging drug, the tolerance to remimazolam in benzodiazepine-taking patients has been unclear.
Yasuhiro Maehara, Osamu Nagata
exaly   +2 more sources

Remimazolam versus Sevoflurane for Paediatric Circumcision: A Randomised Controlled Trial Evaluating Emergence Delirium [PDF]

Drug Design, Development and Therapy
Yi Zhang,1 Shuang Guo,1 Linyun Wang,2 Qingjun Zeng,1 Haishan Cui,1 Yunbo Mo3 1Department of Anesthesiology, Maternal and Child Health Hospital of Wanzhou District, Chongqing, People’s Republic of China; 2Nursing Department, Maternal and Child Health ...
Zhang Y, Guo S, Wang L, Zeng Q, Cui H, Mo Y   +5 more
doaj   +2 more sources

Sex-related differences in blood concentrations and emergence profiles following total intravenous anesthesia with remimazolam and remifentanil [PDF]

Scientific Reports
Remimazolam is a novel, short-acting benzodiazepine, which is characterized by rapid onset and quick recovery. The clinical efficacy and metabolism of many intravenous anesthetics are known to be influenced by sex; however, the effects of sex on the ...
Riko Sato, Hitoshi Higuchi, Yukiko Nishioka, Saki Miyake, Takuya Miyawaki   +4 more
doaj   +2 more sources

The effect of obstructive jaundice on the sensitivity of intravenous anesthetic of remimazolam: study protocol for a controlled multicenter trial

Trials, 2022
Background It is well known that obstructive jaundice could affect the pharmacodynamics of some anesthetics, and the sensitivity of some anesthetics would increase among icteric patients. Remimazolam is a new ultra-short-acting intravenous benzodiazepine
Wen Liu, Bin Yang, Jun-Wei Ji, Hua Yang, Hong-Hao Song, Hai-Bo Qiu, Jin-Chao Song   +6 more
doaj   +1 more source

Safety and efficacy of remimazolam besylate in patients undergoing colonoscopy: A multicentre, single-blind, randomized, controlled, phase Ⅲ trial

Frontiers in Pharmacology, 2022
Study objective: The objective of the study was to evaluate the safety and efficacy of remimazolam besylate versus propofol injection in patients undergoing colonoscopy.Design: A multicenter, randomized, non-inferiority, single-blind, parallel-controlled
Ximei Wang, Xiaolei Hu, Nianyue Bai, Lie Li, Lie Li, Min Zhang, Zhigang Cheng, Qulian Guo   +7 more
doaj   +1 more source

Efficacy and safety of remimazolam besilate for sedation in outpatients undergoing impacted third molar extraction: a prospective exploratory study

BMC Oral Health, 2023
Background Dental treatments often cause anxiety, fear, and stress in patients. Intravenous sedation is widely used to alleviate these concerns, and various agents are employed for sedation.
Kana Oue, Aya Oda, Yoshitaka Shimizu, Tamayo Takahashi, Hisanobu Kamio, Utaka Sasaki, Serika Imamura, Eiji Imado, Akari Mukai, Mitsuru Doi, Miyuki Sakuma, Shigehiro Ono, Tomonao Aikawa, Mitsuhiro Yoshida   +13 more
doaj   +1 more source

Remimazolam Has Low Oral Bioavailability and No Potential for Misuse in Drug-Facilitated Sexual Assaults, with or Without Alcohol: Results from Two Randomised Clinical Trials

Drugs in R&D, 2020
Background and Objectives Remimazolam is a new ultra-short-acting benzodiazepine currently being developed for intravenous use in procedural sedation, general anaesthesia, and intensive care unit sedation.
Marija Pesic, Thomas Stöhr, Joachim Ossig, Keith Borkett, Martin Donsbach, Van-Anh Dao, Lynn Webster, Frank Schippers   +7 more
doaj   +1 more source

Total intravenous anesthesia management with simultaneous use of remimazolam and propofol: A case series of three patients

SAGE Open Medical Case Reports, 2023
Remimazolam is an ultra-short-acting benzodiazepine anesthetic agent. Because of pharmacodynamic interactions in the sedation effect between benzodiazepines and propofol, the combination of remimazolam and propofol may allow for a dose reduction of each ...
Yuki Watanabe, Shinju Obara, Satoki Inoue   +2 more
doaj   +1 more source

Remimazolam Anesthesia for MitraClip Implantation in a Patient with Advanced Heart Failure

Case Reports in Anesthesiology, 2021
Remimazolam, a novel and ultrashort-acting benzodiazepine, has been available for general anesthesia in Japan. The administration of remimazolam does not induce injection pain, has been reported to have less cardiovascular depressant effects during ...
Tomoe Satoh, Noriaki Nishihara, Yasuaki Sawashita, Sho Ohno, Naoyuki Hirata, Michiaki Yamakage   +5 more
doaj   +1 more source