Efficacy and Safety of Remimazolam in Endoscopic Sedation—A Systematic Review and Meta-Analysis [PDF]
Frontiers in Medicine, 2021 Background: The aim of this systematic review and meta-analysis was to investigate the efficacy and safety of remimazolam in clinical endoscopic procedure sedation.Methods: The authors searched the databases of PubMed, Embase, and Cochrane Library for ...
Xianlin Zhu, Hongbai Wang, Su Yuan
exaly +4 more sources
Development and analysis of a remimazolam pharmacokinetics and pharmacodynamics model with proposed dosing and concentrations for anaesthesia and sedation [PDF]
British Journal of AnaesthesiaBackground: Pharmacokinetic–pharmacodynamic (PK–PD) models of remimazolam and their covariate relationships are useful for understanding drug disposition and predicting drug effects.
Douglas J Eleveld +2 more
exaly +4 more sources
The effect of obstructive jaundice on the sensitivity of intravenous anesthetic of remimazolam: study protocol for a controlled multicenter trial [PDF]
Trials, 2022 Background It is well known that obstructive jaundice could affect the pharmacodynamics of some anesthetics, and the sensitivity of some anesthetics would increase among icteric patients. Remimazolam is a new ultra-short-acting intravenous benzodiazepine
Wen Liu +6 more
doaj +2 more sources
Pharmacokinetic properties of remimazolam in subjects with hepatic or renal impairment [PDF]
British Journal of Anaesthesia, 2021 BACKGROUND: Remimazolam is a new benzodiazepine for procedural sedation and general anaesthesia. The aim of this study was to characterise its pharmacokinetic properties and safety in renally and hepatically impaired subjects.
Thomas Stöhr +2 more
exaly +3 more sources
Three cases of difficulty in achieving definitive loss of consciousness with remimazolam
JA Clinical Reports, 2022 Background Remimazolam is a novel, ultra-short-acting benzodiazepine used for general anesthesia. Because remimazolam is an emerging drug, the tolerance to remimazolam in benzodiazepine-taking patients has been unclear.
Osamu Nagata
exaly +2 more sources
Frontiers in Medicine, 2022 ObjectiveHypotension is common in propofol anesthesia. Whether remimazolam could reduce intraoperative hypotension remains unknown. We therefore tested the primary hypothesis that remimazolam reduces the incidence of intraoperative hypotension compared ...
Yuwei Qiu +6 more
doaj +2 more sources
Remimazolam: back to the future [PDF]
Minerva AnestesiologicaRemimazolam can be considered a new anesthetic and sedative drug with broad prospects for use in various procedures across multiple clinical settings, including operating theaters, intensive care units, and non-operating room suites. It seems to have an excellent profile in terms of safety and efficacy for use by anesthesiologists, non-anesthesia ...
Di Filippo, Alessandro +1 more
core +4 more sources
Sex-related differences in blood concentrations and emergence profiles following total intravenous anesthesia with remimazolam and remifentanil [PDF]
Scientific ReportsRemimazolam is a novel, short-acting benzodiazepine, which is characterized by rapid onset and quick recovery. The clinical efficacy and metabolism of many intravenous anesthetics are known to be influenced by sex; however, the effects of sex on the ...
Riko Sato +4 more
doaj +2 more sources
Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD [PDF]
Advanced ScienceAutism spectrum disorder (ASD) is a neurodevelopmental disorder, characterized by social dysfunction and stereotypic behavior, with the neuronal excitation/inhibition (E/I) imbalance as an underlying mechanism.
Yuxin Zhang +7 more
doaj +2 more sources
BMC AnesthesiologyObjective The purpose of this study is to observe whether there is a difference in the anesthetic effect of remimazolam tosilate and remimazolam besylate in daytime hysteroscopic surgery, so as to provide reference for clinical application. Methods Fifty
Huan Zhang +6 more
doaj +3 more sources