Results 41 to 50 of about 2,564 (175)

Review of remimazolam and sedatives in the intensive care unit [PDF]

, 2022
Remimazolam is a novel intravenous ultra-short acting benzodiazepine that has the potential of being a safe and effective new sedative for use in intensive care unit (ICU) settings.
Hey-Ran Choi, In-Ae Song
core   +1 more source

Exploring the Utility of remimazolam in cesarean sections under general anesthesia: A preliminary retrospective analysis and Implications for future study

Heliyon
Background: Remimazolam has recently been introduced as a maintenance agent for general anesthesia. However, the effect of remimazolam on peripartum prognosis has not been reported.
Eunji Ko, Sung Uk Choi, Jaehee Lee, Eun-Saem Choi, Yoon Sun Park   +4 more
doaj   +1 more source

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

Advanced Science, Volume 13, Issue 23, 23 April 2026.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu   +13 more
wiley   +1 more source

Effects of thapsigargin on remimazolam-induced calcium elevation.

, 2022
(A) Following the administration of 5 μM thapsigargin (TG), a Ca2+-ATPase inhibitor (①), the [Ca2+]i was elevated in SHSY-5Y cells. Subsequently, remimazolam at 300 μM was administered 30 min after the TG administration (②).
Soma Noguchi (12029730), Soshi Narasaki (12029724), Yasuo M. Tsutsumi (12029733), Norio Sakai (185474), Kazue Uchida (12029727), Yuhki Yanase (3960317), Tomoaki Urabe (12029718), Hirotsugu Miyoshi (12029721), Michihiro Hide (3960314)   +8 more
core   +1 more source

Investigation of the actual implementation of “post‐sedation discharge criteria” and “time‐out” immediately before procedure in endoscopy: A nationwide survey study in Japan

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Post‐sedation discharge criteria for outpatient endoscopy and time‐out procedures immediately before endoscopic examinations are important for ensuring patient safety. This study used a web‐based questionnaire to survey the implementation status and current situation of these practices in Japan in 2024.
Atsushi Imagawa, Motohiko Kato, Junko Koyama, Mitsuhiro Fujishiro   +3 more
wiley   +1 more source

Bibliometric Analysis of Global Trends in Remimazolam-Related Research Over the Past 15 Years: Compared with Propofol

, 2023
Xinyue Hu, Beibei Wang, Li Hu, Dong Han, Jing Wu Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of ChinaCorrespondence: Jing Wu, Department of ...
Wu J, Wang B, Hu X, Hu L, Han D
core  

Remimazolam for anaesthesia or sedation

, 2020
Purpose of review Anaesthesia and sedation are ubiquitous in contemporary medical practice. Developments in anaesthetic pharmacology are targeted on reducing physiological disturbance whilst maintaining or improving titrateability, recovery profile and ...
Ann E. Rigby-Jones, Sneyd, J. Robert, J. Robert Sneyd, Rigby-Jones, Ann E.   +3 more
core   +1 more source

Comparison of the anesthetic effects of remimazolam tosilate and remimazolam besylate in daytime hysteroscopic surgery

BMC Anesthesiology
Objective The purpose of this study is to observe whether there is a difference in the anesthetic effect of remimazolam tosilate and remimazolam besylate in daytime hysteroscopic surgery, so as to provide reference for clinical application. Methods Fifty
Huan Zhang, Min Fu, Fangli Yue, Yaxin Wei, Xinyuan Shi, Shiyu Yu, Fanceng Ji   +6 more
doaj   +1 more source

Two cases of circulatory collapse due to suspected remimazolam anaphylaxis

JA Clinical Reports, 2022
Background Remimazolam was approved in Japan in January 2020. We report two cases of circulatory collapse due to suspected remimazolam anaphylaxis during anesthetic induction. Case presentation Case 1: A 74-year-old male was scheduled for debridement and
Satoshi Uchida, Daiki Takekawa, Masato Kitayama, Kazuyoshi Hirota   +3 more
doaj   +1 more source

When Endoscopic Sedation is Not an Option: Insights From a Multicenter on‐site Survey on Tolerance for Japanese Gastric Cancer Screening

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Esophagogastroduodenoscopy (EGD) is widely used for gastric cancer (GC) screening in Japan; however, sedation during EGD is not recommended. We aimed to assess the tolerability of unsedated EGD (USEGD) in the Japanese population. Methods Participants who underwent GC screening in Japanese urban areas between July 2021 and December ...
Kazuya Inoki, Toshiya Chiba, Kazuhiro Miura, Teppei Tagawa, Yutaka Aoyagi, Yoshiaki Takeuchi, Naoya Moriyama, Kensuke Kuraoka, Tadashi Ohara, Yuko Haruhara, Akira Mizuki, Jun Satio, Yoshimi Hagisawa, Naomi Ono, Noboru Takayama, Takeo Onishi, Akira Mishima, Norihiro Suzuki, Kazuo Kikuchi, Atsushi Katagiri, Fuyuhiko Yamamura, Sachiko Ohde, Eisuke Inoue, Takahisa Matsuda, Hitoshi Yoshida   +24 more
wiley   +1 more source