Results 51 to 60 of about 2,564 (175)

Remimazolam: Patient satisfaction and safety for procedural sedation

, 2023
Remimazolam je novi intravenski anestetik iz skupine benzodiazepina. Molekularna struktura remimazolama omogućuje mu poseban farmakokinetički profil te ga izdvaja od drugih lijekova u istoj skupini.
Kovač, Nataša, Vučić, Marinko, Ožegić, Ognjen, Bodulica, Bruna, Pažur, Iva, Radočaj, Tomislav, Škrtić, Matteo, Lijović, Lada, Periša, Nikola   +8 more
core   +1 more source

Remimazolam attenuated lipopolysaccharide-induced behavioral deficits and neuronal injury via activation of the Nrf2 pathway

Scientific Reports
Sepsis is a severe disorder that is always accompanied by brain injury and dysfunction. This study aimed to evaluate the effects of remimazolam, a new ultra-short-acting sedative, on LPS-induced neuronal injury, and the role of Nrf2 signaling pathway ...
Yi Wei, Sining Pan, Zhan Zhou, Ying Yang, Tianxiao Liu, Jing Chen, Yubo Xie   +6 more
doaj   +1 more source

Adverse Events of Single Balloon Enteroscopy‐assisted Endoscopic Retrograde Cholangiopancreatography in the Elderly: A Propensity Score Matching Analysis

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background Sedation for conventional endoscopic retrograde cholangiopancreatography (ERCP) has been reported to be safe even for elderly patients. However, the safety of sedation for balloon enteroscopy‐assisted ERCP (BE‐ERCP) has not been well‐studied in the elderly.
Hiroki Nakagawa, Tsuyoshi Takeda, Takeshi Okamoto, Takafumi Mie, Takaaki Furukawa, Takashi Sasaki, Masato Ozaka, Takahisa Matsuda, Yoshinori Igarashi, Naoki Sasahira   +9 more
wiley   +1 more source

Efficacy and Safety of Remimazolam Compared to Midazolam for Sedation During Endoscopic Ultrasonography: A Single‐Center Retrospective Cohort Study

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Remimazolam is a novel ultra–short‐acting benzodiazepine that may offer advantages over conventional sedatives in endoscopic procedures. Evidence for its use in pancreatobiliary endoscopic ultrasonography (EUS) is limited. We compared the efficacy and safety of remimazolam and midazolam in outpatient pancreatobiliary EUS.
Haruka Toyonaga, Makoto Masaki, Hajime Yamazaki, Arata Oka, Yoshiki Matsuno, Hidetoshi Nakata, Shoji Takayama, Tatsuya Nakagawa, Takuya Takayama, Masahiro Orino, Hironao Matsumoto, Kimi Sumimoto, Masahiro Takeo, Norimasa Fukata, Takeshi Yamashina, Masaaki Shimatani, Makoto Naganuma   +16 more
wiley   +1 more source

Remimazolam – current status, opportunities and challenges

, 2023
The short acting benzodiazepine remimazolam has been well characterised for use during procedural sedation. Onset of hypnotic effect is swifter than midazolam and recovery is faster with a period of antegrade amnesia. Haemodynamic changes associated with
Sneyd, J. Robert
core   +1 more source

Association Between American Society of Anesthesiologists Physical Status Classification System and Remimazolam Sedation Outcomes

Academic Emergency Medicine, Volume 33, Issue 4, April 2026.
ABSTRACT Background Remimazolam (RM) is an ultrashort‐acting benzodiazepine with pharmacodynamic properties ideal for procedural sedation in emergency departments (EDs). This study evaluated the safety of RM when used for procedural sedation of American Society of Anesthesiologists (ASA) I–III patients in the ED. Aims To compare the occurrence of no or
Caroline H. Brynning, Simone P. Busch, Anne L. Krarup, Dorte Melgaard   +3 more
wiley   +1 more source

Interventions to prevent postoperative neurocognitive complications: an umbrella review of meta‐analyses of randomised controlled trials

Anaesthesia, Volume 81, Issue 4, Page 532-540, April 2026.
Summary Introduction The certainty of the effectiveness of interventions to manage postoperative neurocognitive complications remains unclear. The objective of this umbrella review was to synthesise and evaluate the evidence for interventions aimed at reducing the incidence of peri‐operative neurocognitive complications.
Filippo D'Amico, Stefano Turi, Marco Manazza, Giuliana Lo Bianco, Giacomo Monti, Alberto Zangrillo, Giovanni Landoni, Luigi Beretta   +7 more
wiley   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, Volume 3, Issue 1, March 2026.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Anesthetic Strategies for Closed Reduction of Dislocated Total Hip Arthroplasty: A Scoping Review

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 3, March 2026.
ABSTRACT Background Total hip arthroplasty (THA) is a frequently performed orthopedic procedure, with dislocation being a common complication, often requiring closed reduction. Anesthetic strategies for this vary, and evidence on the efficacy, safety, and cost‐effectiveness of current strategies is limited.
Rasmus Linnebjerg Knudsen, Rikke Helene Frølund Bjulf, Aurelien‐Xuan Rosendal Bahuet, Mathias Therkel Steensbæk, Anne‐Sofie Linde Jellestad, Kai Henrik Wiborg Lange, Lars Hyldborg Lundstrøm, Anders Kehlet Nørskov   +7 more
wiley   +1 more source

Comparison of remimazolam and midazolam for sedation during colonoscopy in Japanese patients: A propensity score matching analysis

DEN Open
Objectives To compare the efficacy and safety of sedation with midazolam and remimazolam for colorectal endoscopy. Methods This single‐center, two‐arm, post‐hoc analysis of the REM‐IICTJP01 study investigated the efficacy and safety of remimazolam for ...
Kanako Ogura, Ryoji Ichijima, Hisatomo Ikehara, Tomomi Sugita, Daisuke Yamaguchi, Yasuhiko Nagata, Mitsuru Esaki, Yosuke Minoda, Hiroyuki Ono, Kinichi Hotta, Shinsuke Kiriyama, Tetsuya Sumiyoshi, Yuichi Kanmura   +12 more
doaj   +1 more source