Results 41 to 50 of about 12,794 (158)

Tailoring drug‐to‐lipid ratio in redox‐responsive lipid‐mimetic prodrug liposomes for superior cabazitaxel delivery and antitumor efficacy

BMEMat, EarlyView.
Redox‐responsive lipid‐mimetic prodrug liposomes with high drug‐to‐lipid ratios enhance cabazitaxel delivery, prolong circulation, and enable tumor‐selective drug release for superior antitumor efficacy and safety. Abstract Liposomes represent one of the most extensively investigated nanocarriers in drug delivery.
Shengyao Xu, Danping Wang, Si Zheng, Zhiyu Kuang, Ya Gao, Haiyu Zhao, Lurong Zhang, Jiayu Guo, Jingyi Zhang, Weiyao Li, Anhua Wang, Hongrui Lei, Zhonggui He, Ken‐ichiro Kamei, Jianzhao Niu, Lingyun Ma, Bingjun Sun   +16 more
wiley   +1 more source

Anti-Data Leakage Pipeline for Differentiated Thyroid Cancer Recurrence Prediction: Integrating SMOTE, Optuna-based Optimization, and Bootstrap BCa Validation

Journal of Applied Informatics and Computing
Thyroid cancer recurrence prediction remains a critical clinical challenge, as early identification of high-risk patients enables targeted monitoring and intervention.
Deri Rosadi, Sindhu Rakasiwi
doaj   +1 more source

The median effective analgesic concentration of ropivacaine in ultrasound-guided interscalene brachial plexus block after arthroscopic rotator cuff repair

Frontiers in Pharmacology, 2022
Background: The median effective analgesic concentration (MEAC) of ropivacaine in interscalene brachial plexus block (ISBPB) for postoperative analgesia after arthroscopic rotator cuff repair (ARCR) has not been determined. Therefore, this study aimed to
Cheng Xu, Fei Gu, Yang Liu, Rui Chen, Chengyu Wang, Jie Lu   +5 more
doaj   +1 more source

The prevalence of Streptococcus equi subsp. equi carriers in the Netherlands

Equine Veterinary Journal, EarlyView.
Abstract Background Streptococcus equi subspecies equi (S. equi) carriers are thought to be important drivers for strangles outbreaks. Limited data are available on the prevalence of carriers in European horse husbandry settings. Objectives To estimate the prevalence of S.
R. M. A. C. Houben, E. M. Broens, M. J. Broekhuizen‐Stins, M. M. Sloet van Oldruitenborgh‐Oosterbaan, C. van Maanen, J. A. P. Heesterbeek   +5 more
wiley   +1 more source

Roux‐en‐Y gastrojejunostomy and jejunojejunostomy for pyloric obstruction bypass in a horse and a foal

Equine Veterinary Journal, EarlyView.
Abstract Background Gastric outflow obstruction in horses is a rare but challenging condition, often resulting from either congenital anomalies or acquired lesions such as chronic ulceration or pyloric polyps. Conventional surgical bypass procedures, including gastrojejunostomy (GJ) or gastroduodenostomy and less commonly duodenojejunostomy, can ...
Marco Gandini, Nico Bolz, Christian Czech, Myria Hartman, Gessica Giusto   +4 more
wiley   +1 more source

Inferring Relationship of Blood Metabolic Changes and Average Daily Gain With Feed Conversion Efficiency in Murrah Heifers: Machine Learning Approach

Frontiers in Veterinary Science, 2020
Machine learning algorithms were employed for predicting the feed conversion efficiency (FCE), using the blood parameters and average daily gain (ADG) as predictor variables in buffalo heifers.
Poonam Sikka, Abhigyan Nath, Shyam Sundar Paul, Jerome Andonissamy, Dwijesh Chandra Mishra, Atmakuri Ramakrishna Rao, Ashok Kumar Balhara, Krishna Kumar Chaturvedi, Keerti Kumar Yadav, Sunesh Balhara   +9 more
doaj   +1 more source

Single‐stage orthognathic correction of campylorrhinus lateralis in foals using transection and fixation: Surgical description and outcome of four horses

Equine Veterinary Journal, EarlyView.
Abstract Background Campylorrhinus lateralis (‘wry nose’) is a rare congenital maxillofacial deformity of foals resulting in compromise of the airway and severe class 4 malocclusion. Various surgical techniques to correct the deformity have been described, but contemporary data on single‐stage transection and fixation, including use of a rib graft, and
Helio Vasco, Jim Schumacher, Jack Easley
wiley   +1 more source

Exercise with fasting or isotonic drink? A randomized controlled trial in youth elite basketball players

Journal of the International Society of Sports Nutrition
Background Pre-exercise carbohydrate intake is known to influence performance; however, data describing their effect on cardiorespiratory parameters is scarce.
Petra Márton, Luca Kata Bátai, Titanilla Takács, Emese Csulak, Anna Réka Kiss, Bence Kopper, Liliána Erzsébet Szabó, Dorottya Balla, Iván Petrov, Lilla Lázár, Hajnalka Vágó, Béla Merkely, Nóra Sydó   +12 more
doaj   +1 more source

Warmed intravenous fluid administration attenuated a reduction in body temperature in anaesthetised horses

Equine Veterinary Journal, EarlyView.
Abstract Background Peri‐anaesthetic hypothermia is a well‐documented complication of general anaesthesia and is associated with prolonged recovery, impaired wound healing, and delayed coagulation. Fluid warmers can be used to mitigate heat loss, but there is little evidence supporting their effectiveness in equine anaesthesia.
Miranda P. Starr, Alycia Frampton, Allison Mika, Klaus Hopster, Hope Douglas   +4 more
wiley   +1 more source

A Semismooth Newton-Based Augmented Lagrangian Algorithm for the Generalized Convex Nearly Isotonic Regression Problem

Mathematics
The generalized convex nearly isotonic regression problem addresses a least squares regression model that incorporates both sparsity and monotonicity constraints on the regression coefficients.
Yanmei Xu, Lanyu Lin, Yong-Jin Liu
doaj   +1 more source