Results 21 to 30 of about 12,794 (158)

Isotonic regression analysis of Guzerá cattle growth curves

open access: yesRevista Ceres
The objective of this study was to apply data transformation via isotonic regression in growth curves studies of Guzerá cattle whose data presented disturbances characterized by decreased body weight in certain age groups.
Adriano Rodrigues   +5 more
doaj   +1 more source

CVXR: An R Package for Disciplined Convex Optimization

open access: yesJournal of Statistical Software, 2020
CVXR is an R package that provides an object-oriented modeling language for convex optimization, similar to CVX, CVXPY, YALMIP, and Convex.jl. It allows the user to formulate convex optimization problems in a natural mathematical syntax rather than the ...
Anqi Fu   +2 more
doaj   +1 more source

Isotonic and Convex Regression: A Review of Theory, Algorithms, and Applications

open access: yesMathematics
Shape-restricted regression provides a flexible framework for estimating an unknown relationship between input variables and a response when little is known about the functional form, but qualitative structural information is available. In many practical
Eunji Lim
doaj   +1 more source

Determining the Minimum Effective Concentration of Ropivacaine in Epidural Anesthesia for Tolerable Pain in Transforaminal Percutaneous Endoscopic Lumbar Discectomy to Avoid Nerve Injury: A Double-Blind Study Using a Biased-Coin Design

open access: yesDrug Design, Development and Therapy, 2022
Bingwei Hu,1,2 Liang Li,2 Hongwei Wang,2 Tingting Ma,2 Zhimei Fu,2 Xianhui Kang,3 Zhiying Feng1 1Department of Pain, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 2Department of ...
Hu B   +6 more
doaj  

Mitigating Algorithmic Bias Through Probability Calibration: A Case Study on Lead Generation Data

open access: yesMathematics
Probability calibration is commonly utilized to enhance the reliability and interpretability of probabilistic classifiers, yet its potential for reducing algorithmic bias remains under-explored.
Miroslav Nikolić   +4 more
doaj   +1 more source

Regression with Ordered Predictors via Ordinal Smoothing Splines

open access: yesFrontiers in Applied Mathematics and Statistics, 2017
Many applied studies collect one or more ordered categorical predictors, which do not fit neatly within classic regression frameworks. In most cases, ordinal predictors are treated as either nominal (unordered) variables or metric (continuous) variables ...
Nathaniel E. Helwig, Nathaniel E. Helwig
doaj   +1 more source

The EC of remifentanil to minimize the cardiovascular changes during head holder pinning in neurosurgery [PDF]

open access: yesKorean Journal of Anesthesiology, 2012
BackgroundDuring neuroanesthesia, head holder pinning commonly results in sympathetic stimulation manifested by hemodynamic changes, such as increased heart rate and arterial blood pressure.
Wang Seok Do   +3 more
doaj   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

open access: yesAdvanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu   +7 more
wiley   +1 more source

Tailored Covalent Organic Frameworks Enable the Encapsulation of Living Cells to Produce Rare Ginsenoside

open access: yesAdvanced Science, EarlyView.
This work reports the in situ fabrication of Escherichia coli@covalent organic frameworks (E. coli@COFs) in phosphate‐buffered saline. The COFs form an exoskeleton on E. coli, protecting intracellular β‐glucosidase (Ssbgl) while enhancing mass transfer.
Fengmei Liu   +6 more
wiley   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

open access: yesAdvanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu   +7 more
wiley   +1 more source

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