Results 51 to 60 of about 823,086 (268)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Clinical Kidney Journal, 2012 Gastrointestinal side effects affect ∼20% of renal transplant recipients [1]. Among such side effects, diarrhoea is common [2] but under-recognized [3]. Diarrhoea may relate to immunosuppressive drugs or infectious complications. The latter may be caused by one of the usual microbial pathogens that also cause gastroenteritis in immunocompetent patients,
Meyrier, A. +3 more
openaire +2 more sources
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Impact of Demand Side Response on a Commercial Retail Refrigeration System
Energies, 2018 The UK National Grid has placed increased emphasis on the development of Demand Side Response (DSR) tariff mechanisms to manage load at peak times. Refrigeration systems, along with HVAC, are estimated to consume 14% of the UK’s electricity and could ...
Ibrahim M. Saleh +6 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
MENINGKATKAN ADAPTASI AIR MELALUI PERMAINAN AMPAR-AMPAR BOLA PADA TK BINA CITRA CENDEKIA
Active: journal of physical education, sport, health and recreation, 2015 The aim of the research is to improve the adaptation of children in the water via Ampar-Ampar ball game, eliminating the fear of children in the pool, increase the interest and motivation of the child to the pool, assist teachers in teaching swimming ...
Musyarofatul Hadiyatullah +2 more
doaj
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
On the modeling of bending perturbations of melt jets under reactor vessel water pool during severe accident at NPP [PDF]
Ядерна фізика та енергетика, 2009 The given paper presents the modeling results of the bending melt jet perturbations in a coolant pool and disintegration of the jets on drops. It was shown that among the problems requiring studies for the improvement of the passive protection systems ...
Vahid Hasani Moghaddam, I. V. Kazachkov
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source