Results 41 to 50 of about 121,707 (346)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
The Influence of Pressure on Local Heat Transfer Rate under the Vapor Bubbles during Pool Boiling [PDF]
, 2023 Vladimir Serdyukov +2 more
openalex +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Fluids, 2022 Pool boiling surface modification by pin fin array has demonstrated a practical but effective cooling enhancement. Whilst the main challenge is to determine the best configuration of the pin fin dimensions and positioning, it is known that the result ...
Indro Pranoto +2 more
doaj +1 more source
Transient pool boiling in microgravity [PDF]
International Journal of Heat and Mass Transfer, 1992 Transient nucleate pool boiling experiments using R113 are conducted for short times in microgravity and in earth gravity with different heater surface orientations and subcoolings. The heating surface is a transparent gold film sputtered on a quartz substrate, which simultaneously provides surface temperature measurements and permits viewing of the ...
Ervin, Jamie S. (Jamie Steven) +3 more
openaire +2 more sources
Advanced Engineering Materials, EarlyView.This study investigates laser metal deposition of aluminum alloys EN AW‐7075 and EN AW‐5083, using powder blending to compensate zinc and magnesium evaporation. In situ alloying and ex situ alloying with ZnAl12 and AZ91 preserve near‐standard compositions and improve mechanical properties.
Finn Bendixen +3 more
wiley +1 more source
Comparison of heat transfer coefficients of open micro-channels and plain micro-fins
EPJ Web of Conferences, 2018 The paper describes results of analysis of pool boiling heat transfer on enhanced surfaces. Two types of structural surfaces were used: open microchannel surfaces consisting of a system of parallel micro-channels 0.3 mm wide, from 0.2 to 0.5 mm deep and ...
Kaniowski Robert, Pastuszko Robert
doaj +1 more source
Pool Boiling Enhanced by Electric Field Distribution in Microsized Space [PDF]
, 2014 This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014) +1 more
core
Advanced Functional Materials, EarlyView.This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer +7 more
wiley +1 more source