Results 41 to 50 of about 440,241 (267)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Direct Numerical Simulation and Visualization of Subcooled Pool Boiling
Science and Technology of Nuclear Installations, 2014 A direct numerical simulation of the boiling phenomena is one of the promising approaches in order to clarify their heat transfer characteristics and discuss the mechanism.
Tomoaki Kunugi, Yasuo Ose
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Comparison of heat transfer coefficients of open micro-channels and plain micro-fins
EPJ Web of Conferences, 2018 The paper describes results of analysis of pool boiling heat transfer on enhanced surfaces. Two types of structural surfaces were used: open microchannel surfaces consisting of a system of parallel micro-channels 0.3 mm wide, from 0.2 to 0.5 mm deep and ...
Kaniowski Robert, Pastuszko Robert
doaj +1 more source
Fluids, 2022 Pool boiling surface modification by pin fin array has demonstrated a practical but effective cooling enhancement. Whilst the main challenge is to determine the best configuration of the pin fin dimensions and positioning, it is known that the result ...
Indro Pranoto +2 more
doaj +1 more source
A Multi‐Scale Machine Learning Framework for the Inverse Design of High Entropy Alloys
Advanced Engineering Materials, EarlyView.High‐entropy alloys offer vast potential for various applications, including electrocatalysis; however, their compositional complexity challenges conventional screening. We introduce an inverse‐design framework combining two neural networks to determine optimal compositions and reconstruct nanoparticle geometry from targeted properties and conventional
Mikael Takoutsin +14 more
wiley +1 more source
Review of Pool Boiling Enhancement Techniques
NTU Journal of Engineering and TechnologyMany industrial applications recently are utilizing from the pool boiling to treat heat, including power plants, cooling and refrigeration applications, and electronics cooling applications like data centers.
Osamah Altotanje, Nabeel Abdulrazzaq
doaj +1 more source
Advanced Functional Materials, EarlyView.Encapsulation of solid–liquid barocalorics (BC) within MOFs harnesses their colossal BC performance whilst allowing active control of BC properties through BC‐MOF interactions. ABSTRACT Barocaloric (BC) effects at liquid–vapor transitions in hydrofluorocarbons drive most commercial technologies used for heating and cooling in the heating, ventilation ...
Ming Zeng +8 more
wiley +1 more source
Pool Boiling of Novec-649 on Inclined Microchannel
Energies, 2023 Significant amounts of heat flow can be removed with small temperature differences by boiling. This process is used in a variety of industries, e.g., cooling electronics, digital circuits, power sources, etc.
Robert Kaniowski
doaj +1 more source