Results 81 to 90 of about 1,164,954 (301)

FACTORS CONTRIBUTING TO POOR HR PERFORMANCE IN FISCAL ADMINISTRATION [PDF]

open access: yesManagement & Marketing, 2020
The purpose of an employee performance management system within the tax administration is to optimize individual achievements and individual excellence in achieving the strategic objectives, objectives, and subobjectives of ANAF.
Gabriel Ioan AVRĂMESCU
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Nowcast attempts with poor performance due to unfavorable signal-to-noise ratio.

open access: yes, 2014
Nowcast attempts with poor performance due to unfavorable signal-to-noise ratio.
Geoffrey Fairchild (660105)   +4 more
core   +1 more source

Causes of Poor Performance in World Bank Water and Sanitation Projects

open access: yes, 2012
Poor performance affects one in three water and sanitation projects financed by the World Bank. The causes of poor performance in terms of cost, schedule, achievement of objectives, institutional development impact, and sustainability are not well ...
Matsumura, Kristen
core   +2 more sources

The Impact of the Fishing Industry on Boys' Academic Performance: A Case Study of North ‘A’ District in Unguja, Zanzibar, Tanzania

open access: yesEastern African Journal of Humanities and Social Sciences
This study investigates how participation in the fishing industry affects boys’ academic performance in the North “A” District of Zanzibar. It identifies the types of fishing-related activities undertaken by schoolboys, examines the socio-economic ...
Hamide Hemed Amour, Mary Lujabiko Kihupi
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Exploration of the causes of poor performance in mathematics in secondary schools at Thulamahashe Circuit [PDF]

open access: yes, 2022
Thesis (M.Ed. (Curriculum Studies)) -- University of Limpopo, 2022This study investigated the poor performance of learners in mathematics in a rural secondary schools in Bohlabela District in Mpumalanga province. Mathematics is one of the most critical
Mathebula, Mkateko Victoria.
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

The IEA’s poor performance and the risks of oil abundance

open access: yes, 2012
The IEA’s poor performance and the risks of oil abundance / Leonardo Maugeri, Power & Policy, 27/11/2012 http://www.powerandpolicy.com/2012/11/27/the-ieas-poor-performance-and-the-risks-of-oil-abundance Although quite late, the International Energy ...
Danièle Revel
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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