Results 161 to 170 of about 735,101 (274)

Retraction Note: Analysis of the factors influencing moderate to poor performance status in patients with cancer after chemotherapy: a cross-sectional study comparing three models. [PDF]

Sci Rep
Xi K, Jingping L, Yaqing L, Xinyuan Y, Hui L, Mei Y, Qingyue C, Dun L.   +7 more
europepmc   +1 more source

Comparison of Different Tyrosine Kinase Inhibitors for Treatment of Poor Performance Status Patients with EGFR-Mutated Lung Adenocarcinoma. [PDF]

Cancers (Basel), 2022
Wu CE, Chang CF, Huang CY, Yang CT, Kuo CS, Hsu PC, Chang JW.   +6 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

A Novel Approach for Stereotactic Radiosurgery of Multiple Brain Metastasis in a Patient With Poor Performance Status: A Case Report. [PDF]

Case Rep Oncol Med
Iranmehr A, Sheikholeslami S, Banaee N, Shirani M, Farzin M, Jafari F.   +5 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Functional Recovery Following Intensive Upfront Therapy in Multiple Myeloma Patients With Poor Performance Status: A Case Series. [PDF]

J Investig Med High Impact Case Rep
Latif K, Qi J, Shah P, Akhtari M.
europepmc   +1 more source

Anti-PD-1 Monotherapy for Advanced NSCLC Patients with Older Age or Those with Poor Performance Status. [PDF]

Onco Targets Ther, 2021
Matsubara T, Seto T, Takamori S, Fujishita T, Toyozawa R, Ito K, Yamaguchi M, Okamoto T.   +7 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Relationship of Psychiatric Morbidity, Symptom Severity, Performance Status and Social Support with Sleep Quality Among Adult Cancer Patients in Jammu, India: An Institution Based Cross Sectional Study

JK Science
Background: Cancer Patients usually have poor sleep quality, which has detrimental physical and psychological consequences. The present study aimed to assess the relationship between psychiatric morbidity, symptom severity, performance status, and ...
Ritika Chalotra, Rahul Sharma, Rajiv Kumar Gupta, Richa Mahajan, Rashmi Kumari   +4 more
doaj