Results 181 to 190 of about 735,101 (274)

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Sotorasib in Advanced <i>KRAS</i> G12C-Mutated NSCLC: Results From the Global Expanded Access Program, Including Patients With Poor Performance Status and a History of CNS Metastases. [PDF]

JTO Clin Res Rep
Novello S, Rabinovich NM, Shih JY, Pelizzari G, Stevenson J, Majem M, Ferreira CG, Petty WJ, Arriola E, Castagneris N, De Castro J, Morbeck I, Bauman J, Toschi L, Zer A, Metro G, Kalmadi S, Martinez AA, Al Husaini H, Meloni AR, Nduka C, Ardito-Abraham C, Xia C, Awad MM.   +23 more
europepmc   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Expanding the scope of PSMA-RLT: evaluating treatment in challenging mCRPC patients with poor performance status (ECOG 3). [PDF]

Eur J Nucl Med Mol Imaging
Bastian MB, Wörl B, Blickle A, Burgard C, Speicher T, Bartholomä M, Schaefer-Schuler A, Maus S, Ezziddin S, Rosar F.   +9 more
europepmc   +1 more source

MTE27.01 Treatment of Lung Cancer Patients with Poor Performance Status [PDF]

Journal of Thoracic Oncology, 2017
openaire   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Mini-Endoscopic Combined Intrarenal Surgery in Patients with Poor Performance Status: A Retrospective Analysis of Postoperative Fever in Over 1000 Cases. [PDF]

Urol Res Pract
Tabei T, Ito H, Inoue T, Watanab T, Fukuda T, Yamamichi F, Shibata Y, Matsuzaki J, Kobayashi K.   +8 more
europepmc   +1 more source

PC05.02 Are ICIs Effective for Poor Performance Status Patients with Advanced NSCLC? [PDF]

Journal of Thoracic Oncology, 2019
F. Grossi, C. Genova
openaire   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Exploratory Evaluation of the Fibrosis-4 index, Albumin-bilirubin score, and Neutrophil-lymphocyte ratio (FAN) Sepsis Score for Prognosis in Patients With Poor Performance Status and Sepsis Due to Obstruction by Urinary Calculi. [PDF]

Cureus
Iwagami S, Nishihata M, Miyai H.
europepmc   +1 more source