Results 81 to 90 of about 11,868,806 (256)

Population attributable fraction (PAF) among modifiable breast cancer risk factors according to the menopausal status.

, 2018
Population attributable fraction (PAF) among modifiable breast cancer risk factors according to the menopausal status.
Kenneth R. Muir (146404), Artitaya Lophatananon (146409), William Ollier (107701), Kawthar Al-Ajmi (5563043)   +3 more
core   +1 more source

Improving the estimation of the burden of risk factors: an illustrative comparison of methods to measure smoking-attributable mortality [PDF]

, 2015
Background Prevention efforts are informed by the numbers of deaths or cases of disease caused by specific risk factors, but these are challenging to estimate in a population.
Peter Tanuseputro, Deirdre Hennessy, Heather Manson, Kumanan Wilson, Meltem Tuna, Rosella, Laura, Laura Rosella, Bennett, Carol, Manson, Heather, Wilson, Kumanan, Hennessy, Deirdre, Carol Bennett, Douglas Manuel, Richard Perez, Tanuseputro, Peter, Manuel, Douglas, Perez, Richard, Tuna, Meltem   +17 more
core   +2 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Population-Attributable Fraction Using the Marginal Structural Model.

, 2016
Population-Attributable Fraction Using the Marginal Structural Model.
Masataka Taguri (457519), Yoshiki Ishikawa (316176), Hiromu Nishiuchi (316177)   +2 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Population attributable risk of achieving the recommended minimum number of visits for select modifiable factors.

, 2016
Population attributable risk of achieving the recommended minimum number of visits for select modifiable factors.
Marie T. Ruel (2559160), Purnima Menon (2559169), Tuan T. Nguyen (2559163), Lan M. Tran (2559172), Rahul Rawat (404212), Phuong H. Nguyen (525808), Edward A. Frongillo (2282224), Sunny S. Kim (2559157), Nemat Hajeebhoy (2559166)   +8 more
core   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Comparing population attributable risks for heart disease across the adult lifespan in women

, 2015
Background Recent estimates suggest that high body mass index (BMI), smoking, high blood pressure (BP) and physical inactivity are leading risk factors for the overall burden of disease in Australia.
Pavey, Toby, Bauman, Adrian, Bauman, Adrian E., Brown, Wendy J.   +3 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Labour-type physical activity, alcohol use and hypertension in rural older adults in Northeast China

Frontiers in Public Health
BackgroundHypertension is highly prevalent in older adults, yet evidence from resource-limited rural settings remains limited. In Northeast China, older residents are chronically exposed to cold-climate stress, labour-intensive agricultural routines, and
Yongheng Zhao, Yongheng Zhao, Yongheng Zhao, Gaixia Hou, Gaixia Hou, Yimeng Gu, Yimeng Gu, Zhuangzhuang Guo, Zhuangzhuang Guo, Dehui Zhang, Xuefeng Xi, Xuefeng Xi, Limeng Liu, Lizhen Ning, Lizhen Ning, Lizhen Ning, Lizhen Ning   +16 more
doaj   +1 more source