Results 101 to 110 of about 30,535,461 (238)

Older age relates to worsening of fine motor skills: a population-based study of middle-aged and elderly persons

open access: yesFrontiers in Aging Neuroscience, 2014
Introduction: In a population-based study of 1,912 community-dwelling persons of 45 years and older we investigated the relation between age and fine motor skills using the Archimedes spiral-drawing test.
Yoo Young eHoogendam   +14 more
doaj   +1 more source

Effectiveness of lamotrigine in clinical practice: results of a retrospective population-based study. [PDF]

open access: yes, 2005
Contains fulltext : 47617.pdf (Publisher’s version ) (Closed access)OBJECTIVE: Evaluation of the effectiveness of lamotrigine in a population-based cohort of epilepsy patients.
Deckers, C.L.P.   +9 more
core   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Population policy under an arbitrary welfare criterion : theory and issues [PDF]

open access: yes, 1972
For more about the East-West Center, see http://www.eastwestcenter.org/Many well-defined policy problems can be formally described as follows: Let x(t) be an n-dimensional vector describing the state of a system at time t , and y(t) be an m-dimensional ...
Arthur, W. Brian   +1 more
core   +1 more source

Women and HIV: Understanding and addressing stigma—Evidence from the Population Council [PDF]

open access: yes, 2019
Over the last 20 years, the Population Council has carried out extensive work examining the intersection of stigma and gender and its impact on HIV-related outcomes.
Population Council
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Transfers of capital and shifts in New Zealand’s regional population distribution, 1840-1996 [PDF]

open access: yes, 2002
When researchers attempt to study population and development, and particularly the role of migrations, the focus is normally on national level trends, frequently involving time-series analyses of more generic indicators of population change and economic ...
Pool, Ian
core  

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