Results 31 to 40 of about 58,959,543 (293)

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

International incidence of childhood cancer, 2001–10: a population-based registry study

open access: yesThe Lancet Oncology, 2017
Summary Background Cancer is a major cause of death in children worldwide, and the recorded incidence tends to increase with time. Internationally comparable data on childhood cancer incidence in the past two decades are scarce.
E. Steliarova-Foucher   +230 more
semanticscholar   +1 more source

Proinflammation and Hypertension: A Population‐Based Study [PDF]

open access: yesMediators of Inflammation, 2008
There is evidence that proinflammation may be linked to the development of hypertension (HT). We examined the association of both the interleukin‐1 beta (IL‐1β) and the interleukin 1‐receptor antagonist (IL‐1ra) with future blood pressure (BP) and HT occurrence (BP ≥ 140/90 mmHg, or antihypertensive drug) in a population‐based prospective study.
Mauno Vanhala   +2 more
openaire   +3 more sources

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

National population-based estimates for major birth defects, 2010–2014

open access: yesBirth Defects Research, 2019
Background: Using the National Birth Defects Prevention Network (NBDPN) annual data report, U.S. national prevalence estimates for major birth defects are developed based on birth cohort 2010–2014. Methods: Data from 39 U.S.
Cara T. Mai   +10 more
semanticscholar   +1 more source

Venous thromboembolism in cancer patients: a population-based cohort study.

open access: yesBlood, 2020
The incidence of venous thromboembolism in cancer patients may have changed in the past decade, possibly due to novel cancer therapies, improved survival, and high-resolution imaging.
F. Mulder   +8 more
semanticscholar   +1 more source

Population-based Screening in the Era of Genomics [PDF]

open access: yesPersonalized Medicine, 2012
To date, risk profiles based on the known common susceptibility variants have limited value in predicting risk of disease but they could be used for risk stratification in prevention programmes at population level. We illustrate the potential utility of polygenic risk stratification using the case of population-based screening for prostate and breast ...
Nora Pashayan, Paul Pharoah
openaire   +2 more sources

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa   +8 more
wiley   +1 more source

Advances in Population-Based Studies [PDF]

open access: yesStroke, 2010
In 2009, population-based studies have continued to generate many new results about stroke occurrence and interesting hypotheses about the relation between risk factors and stroke occurrence. High levels of C-reactive protein have been associated with the risk of myocardial infarction, whereas the association with stroke remains controversial.1 The ...
openaire   +2 more sources

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

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