Results 121 to 130 of about 10,195,814 (311)

Population-based cohort study on comparative effectiveness and safety of biologics in inflammatory bowel disease

Clinical Epidemiology, 2018
Riccardo Di Domenicantonio,1 Francesco Trotta,1 Silvia Cascini,1 Nera Agabiti,1 Anna Kohn,2 Antonio Gasbarrini,3 Marina Davoli,1 Antonio Addis1 1Department of Epidemiology, Lazio Regional Health Service, Rome, Italy; 2IBD Unit, AO San Camillo Forlanini ...
Di Domenicantonio R, Trotta F, Cascini S, Agabiti N, Kohn A, Gasbarrini A, Davoli M, Addis A   +7 more
doaj  

Prevalence, persistence, and severity of 12-month and 30-day DSM-5 disorders in the World Mental Health Hong Kong StudyResearch in context

The Lancet Regional Health. Western Pacific
Summary: Background: The World Mental Health Hong Kong (WMHHK) Study aims to estimate 12-month and 30-day prevalence, persistence, severity, and correlates of DSM-5 anxiety, mood, and externalising disorders in Hong Kong, a densely populated city ...
Corine S.M. Wong, Candi M.C. Leung, Shiyi Wu, Francis P. Flores, Yoona Kim, Xiao Xiao, Solomon B.K. Wong, Wing Chung Chang, Wai Chi Chan, Nancy Xiaonan Yu, Calvin P.W. Cheng, Albert K.K. Chung, Edwin H.M. Lee, Wai Tat Chiu, William G. Axinn, Ronald C. Kessler, Michael Y. Ni   +16 more
doaj   +1 more source

Association between perceived insufficient sleep, frequent mental distress, obesity and chronic diseases among US adults, 2009 behavioral risk factor surveillance system

BMC Public Health, 2013
Background Although evidence suggests that poor sleep is associated with chronic disease, little research has been conducted to assess the relationships between insufficient sleep, frequent mental distress (FMD ≥14 days during the past 30 days), obesity,
Liu Yong, Croft Janet B, Wheaton Anne G, Perry Geraldine S, Chapman Daniel P, Strine Tara W, McKnight-Eily Lela R, Presley-Cantrell Letitia   +7 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Dyslipidemia in diabetes: a population-based study in Bali

International Journal of General Medicine, 2019
Ketut Suastika,1 I Made Siswadi Semadi,1 I Made Pande Dwipayana,1 Made Ratna Saraswati,1 Wira Gotera,1 Anak Agung Gde Budhiarta,1 Kinuyo Matsumoto,2 Naemi Kajiwara,2 Hiroshi Taniguchi31Division of Endocrinology and Metabolism, Department of Internal ...
Suastika K, Semadi IMS, Dwipayana IMP, Saraswati MR, Gotera W, Budhiarta AAG, Matsumoto K, Kajiwara N, Taniguchi H   +8 more
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Economic Burden of Uncontrolled COPD Under Triple Therapy: A Population-Based Study

International Journal of COPD
Nicolas Molinari,1 Nicolas Roche,2 Anne-Lise Vataire,3 Stanislas Perrier,3 Nicolas Pagès,4 Arnaud Panes,4 Aurélie Schmidt,4 Arnaud Bourdin,5,6 Laurence Watier7 1IDESP, INSERM, PreMEdical INRIA, Univ Montpellier, CHU Montpellier, Montpellier, France ...
Molinari N, Roche N, Vataire AL, Perrier S, Pagès N, Panes A, Schmidt A, Bourdin A, Watier L   +8 more
doaj  

A population-based study of the stratum corneum moisture

Clinical, Cosmetic and Investigational Dermatology, 2016
Thiago de Farias Pires,1 Ana Paula Azambuja,2 Andrea Roseli Vançan Russo Horimoto,1 Mary Sanae Nakamura,2 Rafael de Oliveira Alvim,1 José Eduardo Krieger,1 Alexandre Costa Pereira1 1Laboratory of Genetics and Molecular Cardiology, Heart ...
Pires TF, Azambuja AP, Horimoto AR, Nakamura MS, Alvim RO, Krieger JE, Pereira AC   +6 more
doaj  

Polyethylene glycol and prevalence of colorectal adenomas : Population-based study of 1165 patients undergoing colonoscopy [PDF]

, 2006
Background and aim — Dietary polyethylene glycol (PEG) is extraordinarily potent in the chemoprevention of experimental colon carcinogenesis. PEG is used to treat constipation in France and in the USA. French laxatives include Forlax® (PEG4000), Movicol®
Barbieux, Jean-Pierre, Bertrand, Philippe, Bougnoux, Philippe, Brondin, Brigitte, Corpet, Denis E., Dorval, Etienne, Jankowski, Jean Marie, Viguier, Jérôme   +7 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source