Results 241 to 250 of about 10,120,182 (310)

Metastatic Recurrence of Breast Cancer by Stage and Molecular Profile: A Population-Based Study Among Italian Women. [PDF]

Cancer Med
Giudici F, De Vidi S, Guzzinati S, Toffolutti F, Francisci S, Mariotto AB, Ravaioli A, Botta L, De Angelis R, Bidoli E, Falcini F, Puppo A, Mangone L, Michiara M, Fusco M, Fanetti AC, Andreotti A, Capocaccia R, Serraino D, Dal Maso L, AIRTUM working group.   +20 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Subdomains of Post-COVID Syndrome (PCS) - a population-based study. [PDF]

BMC Infect Dis
Ballhausen-Lübcker S, Ruß AK, Lieb W, Schäfer A, Krist L, Fricke J, Scheibenbogen C, Rabe KF, Maetzler W, Maetzler C, Laudien M, Frank D, Heyckendorf J, Miljukov O, Haeusler KG, El Mokhtari NE, Witzenrath M, Vehreschild JJ, Appel KS, Chaplinskaya-Sobol I, Tamminga T, Nürnberger C, Schmidbauer L, Morbach C, Störk S, Reese JP, Keil T, Heuschmann P, Schreiber S, Krawczak M, Bahmer T.   +30 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Status and trends of early-onset cancers and their risk factors in China: population-based study. [PDF]

J Glob Health
Yun Z, Yang Q, Han X, Wang C, Wang M, Wang Y, Zhang Y, Wang N, Zhang L, Kong F.   +9 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Changes in Depressive Patterns Before and After Lung Cancer Diagnosis: A Nationwide Population-Based Study. [PDF]

Psychooncology
Borg M, Farver-Vestergaard I, Hilberg O, Steed L, Nissen L, Ibsen R, Løkke A.   +6 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source