Results 131 to 140 of about 13,472,802 (342)
Stacks: an analysis tool set for population genomics
Molecular Ecology, 2013 J. Catchen +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Evidence-based Pandemic Preparedness: An Infrastructure for Population-scale Genome-based Testing for COVID-19 [PDF]
, 2021 Hans Lehrach +7 more
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
AZERBAYCAN NÜFUSUNUN EĞİTİM AÇISINDAN ANALİZİ
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2005 Azerbaycan nüfusunun eğitim durumu tarihsel süreç içerisinde çok fazla değişime uğramıştır. Ülke nüfusunun eğitim durumu özellikle Sovyet Döneminden günümüze kadar geçen sürede büyük değişime uğramıştır. Örneğin, 1926 yılında ülke nüfusunun yaklaşık % 30’
Rehman Seferov, Akif Akkuş
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
SALİHLİ’NİN MANİSA NÜFUS ÖZELLİKLERİ
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2008 Araştırma sahasınıoluşturan Salihli, Manisa iline bağlıbir ilçe olup Ege Bölgesi’nin Asıl Ege Bölümü’nde yer alır. Saha 28o10ıve 28o40ıdoğu boylamlarıile 38o20ıve 38o45ıkuzey enlemleri arasında konumlanmıştır.
Ayhan Akış, Hasan Ozan Başkan
doaj
, 2013 This is a summary of my lectures during the 2011 IAC Winter School in Puerto de la Cruz. I give an introduction to the field of stellar populations in galaxies, and highlight some new results. Since the title of the Winter School was {\it Secular Evolution of Galaxies} I mostly concentrate on nearby galaxies, which are best suited to study this theme ...
openaire +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source