Results 61 to 70 of about 14,390,403 (390)
WKB theory of large deviations in stochastic populations [PDF]
Stochasticity can play an important role in the dynamics of biologically relevant populations. These span a broad range of scales: from intra-cellular populations of molecules to population of cells and then to groups of plants, animals and people. Large deviations in stochastic population dynamics - such as those determining population extinction ...
arxiv +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Emotional stress estimation in general population
Despite great deal of popular research interest in existence and altered body responses of emotional stress there are still strong arguments regarding its positive and negative impact on psychophysiological health.
Maria Altaf+4 more
doaj +1 more source
Genetic diversity in introduced populations with Allee effect [PDF]
A phenomenon that strongly influences the demography of small introduced populations and thereby potentially their genetic diversity is the Allee effect, a reduction in population growth rates at small population sizes. We take a stochastic modeling approach to investigate levels of genetic diversity in populations that successfully overcame a strong ...
arxiv
Demographic perspectives in research on global environmental change [PDF]
Human population is at the centre of research on global environmental change. On the one hand, population dynamics influence the environment and the global climate system through consumption-based carbon emissions. On the other hand, health and wellbeing of the population is already being affected by climate change. The knowledge on population dynamics
arxiv
Sexuality education matters: Experiences of youth in Tamil Nadu [PDF]
Serious reservations have been expressed about providing family life or sex education for school-going youth in India. Tamil Nadu is a state in India that had introduced the School AIDS Education Programme in 1997.
International Institute for Population Sciences (IIPS)+1 more
core +1 more source
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard+7 more
wiley +1 more source
Population genetic consequences of the Allee effect and the role of offspring-number variation [PDF]
A strong demographic Allee effect in which the expected population growth rate is negative below a certain critical population size can cause high extinction probabilities in small introduced populations. However, many species are repeatedly introduced to the same location and eventually one population may overcome the Allee effect by chance.
arxiv
Youth in India: Situation and Needs 2006-2007, executive summary, Jharkhand [PDF]
This executive summary presents, in brief, findings on the situation of youth in Jharkhand, part of a subnational study undertaken by the International Institute for Population Sciences, Mumbai, and the Population Council, New Delhi, as part of a project
International Institute for Population Sciences (IIPS)+1 more
core +2 more sources
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung+6 more
wiley +1 more source