Results 71 to 80 of about 13,472,802 (342)

Uncertainty Analysis in Population-Based Disease Microsimulation Models [PDF]

, 2012
Behnam Sharif, Jacek A. Kopec, Hubert Wong, Philippe Finès, Eric C. Sayre, Ran R. Liu, Michael Wolfson   +6 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Risk factors for the occurrence ofEscherichia colivirulence geneseae,stx1andstx2in wild bird populations [PDF]

, 2009
Lesley Hughes, Malcolm J. Bennett, P. A. F. Coffey, Joseph Bailey Elliott, Trevor R. Jones, R.C. Jones, Angela Lahuerta‐Marin, K Mcniffe, David J. Norman, Nicola Williams, Julian Chantrey   +10 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Membranous nephropathy remains the commonest primary cause of nephrotic syndrome in a northern European Caucasian population [PDF]

, 2009
Emily P. McQuarrie, Bruce Mackinnon, G. Stewart, Colin Geddes, On behalf of the Scottish Renal Biopsy Registry   +4 more
openalex   +1 more source

The Bimodal Absorption System Imaging Campaign (BASIC) I. A Dual Population of Low-metallicity Absorbers at z $<1$ [PDF]

, 2022
Michelle A. Berg, Nicolas Lehner, J. Christopher Howk, John M. O’Meara, Joop Schaye, Lorrie A. Straka, Kathy L. Cooksey, Todd M. Tripp, J. X. Prochaska, Benjamin D. Oppenheimer, Sean D. Johnson, Sowgat Muzahid, Rongmon Bordoloi, Jessica K. Werk, Andrew J. Fox, Neal Katz, Martin Wendt, Molly S. Peeples, Joseph Ribaudo, Jason Tumlinson   +19 more
openalex   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Comparative Study of Nutritional Composition, Physiological Indicators, and Genetic Diversity in Litopenaeus vannamei from Different Aquaculture Populations

Biology
This study aimed to evaluate the quality and genetic diversity of farmed Litopenaeus vannamei across three distinct populations from Maoming City (MM), Zhanjiang City (ZJ), and Yangjiang City (YJ) in Guangdong Province. Muscle tissues from L.
Yundong Li, Siyao Cao, Shigui Jiang, Jianhua Huang, Qibin Yang, Song Jiang, Lishi Yang, Falin Zhou   +7 more
doaj   +1 more source

Efficiency of activity of local self-governance bodies in realisation of social policy Эффективность деятельности органов местного самоуправления в реализации социальной политики [PDF]

Problemi Ekonomiki, 2013
The article substantiates theoretical approaches to formation of social policy of Ukraine and increase of efficiency of activity of municipal formations in its realisation.
Ievsieieva Olga A.
doaj  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source