Results 81 to 90 of about 11,560,181 (351)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Migration Statistics, Population Accounts and Life Tables – the Methodology Used in Bulgaria

Migracijske i etničke teme, 2003
Vital statistics in Bulgaria are considered to be comparatively detailed, complete and precise. Professionals at the National Statistical Institute prefer to use these data together with more direct methods to produce life tables with single year age ...
Nikola Tcholakov
doaj  

EFFECT OF SPECIFIC BALANCE STRATEGY TRAINING PROGRAMME ON BALANCE IN INSTITUTIONALIZED ELDERLY POPULATION

International Journal of Physiotherapy, 2015
Background: Balance emerges from the interaction of multiple systems that are organized to meet functional task goals and that are constrained by environmental context, but is often compromised with advancing age.
Muzaffar Mairaj, Hamdani Nusrat, Walia Shefali   +2 more
doaj   +1 more source

Recommendations for a core outcome set for measuring standing balance in adult populations: a consensus-based approach [PDF]

, 2015
Standing balance is imperative for mobility and avoiding falls. Use of an excessive number of standing balance measures has limited the synthesis of balance intervention data and hampered consistent clinical practice.To develop recommendations for a core
A Shumway-Cook, A Shumway-Cook, AA Qutubuddin, AH Newstead, AL Leddy, AL Leddy, Antony Bayer, Brian E. Maki, CF Dillon, CH Wang, CS Tsang, CY Chou, D Donoghue, D Podsiadlo, D Tran, DC Bland, Debra J. Rose, DH Saunders, DJ Rose, DL Sturnieks, DT Felson, F Franchignoni, F Franchignoni, F La Porta, FB Horak, FB Horak, HF Mao, JF Lemay, JM Guralnik, JR Basford, K Berg, K Berg, K Fitch, Kathryn M. Sibley, KJ Brusse, KM Sibley, KM Sibley, KO Berg, KO Berg, LA Beaupre, LA King, LD Gillespie, Liza Stathokostas, LK Boulgarides, M Bergstrom, M Boers, M Conradsson, M Godi, M McGlynn, M Wirz, MA Holbein-Jenny, ME McNeely, ME Tinetti, ME Tinetti, MK Murphy, N Lofgren, P Jogi, PL Scalzo, PR Williamson, R Haas, R Orr, RA Liston, RP Duncan, S O'Hoski, S Whitney, S Wood-Dauphinee, Sarah E. Lamb, SE Lamb, SF Tyson, SF Tyson, Sharon E. Straus, Stephen R. Lord, Susan B. Jaglal, T Crocker, T Steffen, TE Howe, TE Howe, TJ Stevenson, Tracey Howe, UB Flansbjer, V Hiengkaew, Vicky Scott, YC Learmonth   +82 more
core   +4 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Task-dependent Modulation of Cortical Excitability and Balance Control in Individuals with Post-concussion Syndrome [PDF]

, 2017
In most cases, symptoms resolve between 7-10 days post-concussion. However, in 10-15% of the concussed population, symptoms can remain unresolved for months to years following the head injury.
Cinelli, Michael E, Mr, Kalmar, Jayne M, Ms., Kaster, Kristen   +2 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

November Turmoil [PDF]

, 2016
November meant turmoil. It meant upheaval. It meant confusion. Americans had tried to speak in a clear voice, but they were about split down the center. So divided was the nation, there was no clear winner.
Rudy, John M.
core   +1 more source

Dynamics of cancer recurrence

, 2013
Mutation-induced drug resistance in cancer often causes the failure of therapies and cancer recurrence, despite an initial tumor reduction. The timing of such cancer recurrence is governed by a balance between several factors such as initial tumor size ...
Foo, Jasmine, Leder, Kevin
core   +1 more source