Results 61 to 70 of about 7,095,271 (257)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Population Briefs, Vol. 9, no. 2 [PDF]
, 2003 IN THIS ISSUE: Education improves breastfeeding practices in Zambia | Focus on newborn survival needed in rural Pakistan | Hormone choice may reduce risks of menopause therapy | Innovative strategies reduce fertility in Ghana | The future of training ...
Population Council
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Population Council Strategic Plan 2023–2030 [PDF]
, 2022 For 70 years, the Population Council has transformed global thinking on critical health and development issues through our social science, public health, and biomedical research.
Population Council
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MathematicsThis study introduces a novel particle model for biomass fast pyrolysis, incorporating an anisotropic cylindrical particle to address mass and energy transport coupled with aerosol ejection, which previous models have overlooked.
Mario A. Sánchez +4 more
doaj +1 more source
, 2013 In this work a new approach for calculating the rate of formation of polymer nanoparticles in solvent-displacement precipitation processes is presented. The work is motivated by the fact that the standard expressions obtained from the classic nucleation ...
Marchisio, Daniele +3 more
core
Biomedical research at the Population Council [PDF]
, 2015 IN THIS ISSUE: Research and development to improve reproductive health | From bench to bedroom: Biomedical research at the Population Council | Male contraception in discovery | Multipurpose prevention technologies in early-stage development ...
Population Council
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
On aggregative economic models and population policy [PDF]
, 1971 For more about the East-West Center, see http://www.eastwestcenter.org/The aim of this paper is to set out the requirements of a theory of optimal economic--demographic growth. There are three sections.
McNicoll, Geoffrey +1 more
core +1 more source