Results 81 to 90 of about 847,935 (266)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Impact of Wii Fit Training (WFT) and Reactive Balance Training (RBT) for in elder age population: A comparative analysis

open access: yesJournal of Pharmacy and Bioallied Sciences
Objective: This study aims to assess the comparative efficacy of two distinct balancing training intervention strategies, namely, Wii Fit Balance Training (WFT) and Reactive Balance Training (RBT), in reducing older individuals' fear of falling, as well ...
Mazen AlQahtani
doaj   +1 more source

Modeling of Flocculation and Sedimentation Using Population Balance Equation

open access: yesJournal of Chemistry, 2019
Flocculation is a special phenomenon for fine sediment or silt in reservoirs and estuaries. Flocculation usually results in changes of size, morphology, and settling velocity of sediment particles and finally changes of bed topography of reservoirs and ...
Zhipeng Shi   +4 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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