Results 101 to 110 of about 2,630,928 (351)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Applied Population Biology [PDF]

open access: yes, 1992
Population biology and its application to practical problems.- The biology of land restoration.- Genetic conservation in captive populations and endangered species.- Population biology and conservation of rare plants.- Genetics of weed invasions.- Population management in new plant breeding approaches.- The population dynamics and control of the ...
openaire   +1 more source

ADVENTURES IN HUMAN POPULATION BIOLOGY [PDF]

open access: yesAnnual Review of Anthropology, 1996
▪ Abstract  In this professional memoir I trace my career and the changes that occurred after World War II in the biological anthropology studies of human populations. I describe my academic training at the University of New Mexico and Harvard University and my research training at the US Climatic Research Laboratory.
openaire   +2 more sources

The biology and culture of marine bivalve molluscs of the genus Anadara [PDF]

open access: yes
A review of the general biology, ecology, population dynamics, reproduction and culture methods of marine bivalves of the family Arcidae, subfamily Anadarinae.
Broom, M.J.
core  

Stochastic and deterministic models for age-structured populations with genetically variable traits

open access: yes, 2009
Understanding how stochastic and non-linear deterministic processes interact is a major challenge in population dynamics theory. After a short review, we introduce a stochastic individual-centered particle model to describe the evolution in continuous ...
C. Besse   +5 more
core   +3 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Proteomics and Population Biology in the Cardiovascular Health Study (CHS): design of a study with mentored access and active data sharing. [PDF]

open access: yesEur J Epidemiol, 2022
Austin TR   +37 more
europepmc   +1 more source

The contribution of statistical physics to evolutionary biology

open access: yes, 2011
Evolutionary biology shares many concepts with statistical physics: both deal with populations, whether of molecules or organisms, and both seek to simplify evolution in very many dimensions.
Ao   +91 more
core   +1 more source

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