Results 71 to 80 of about 2,626,290 (294)

An Efficient Bayesian Inference Framework for Coalescent-Based Nonparametric Phylodynamics

open access: yes, 2014
Phylodynamics focuses on the problem of reconstructing past population size dynamics from current genetic samples taken from the population of interest.
Karcher, Michael   +4 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Darkedge midshipman Porichthys analis (Batrachoidiformes: Batrachoididae), a common shrimp-bycatch fish from the Gulf of California

open access: yesRevista de Biología Tropical, 2012
Shrimp fishery bycatch of the Gulf of California constitutes a wide variety of highly unknown fish, crustacean, and mollusk species with very low or null economic value, in contrast to those of commercial interest.
Oscar A. González-Ochoa   +2 more
doaj  

Spatiotemporal analysis of the structure and genetic diversity of Stemphylium vesicarium populations in New York onion fields

open access: yesFrontiers in Microbiology
Stemphylium leaf blight (SLB), caused by the hemibiotrophic fungus, Stemphylium vesicarium, is the dominant foliar disease affecting onions in New York (NY), USA.
Aastha Subedi   +5 more
doaj   +1 more source

The Impact of Nucleotide Sequence Analysis on Meningococcal Vaccine Development and Assessment

open access: yesFrontiers in Immunology, 2019
Since it became available as a routine tool in biology, the determination and analysis of nucleotide sequences has been applied to the design of vaccines and the investigation of their effectiveness.
Martin Christopher James Maiden
doaj   +1 more source

Investigation of parental care in avocets from the perspectives of behavioural ecology and conservation biology [PDF]

open access: yes, 2002
This research encompasses both basic (behavioural ecology) and applied (conservation biology) aspects of the biology of Avocets (Recurvirostra avosetta L.).
Lengyel, Szabolcs
core  

The phenotypic equilibrium of cancer cells: From average-level stability to path-wise convergence

open access: yes, 2015
The phenotypic equilibrium, i.e. heterogeneous population of cancer cells tending to a fixed equilibrium of phenotypic proportions, has received much attention in cancer biology very recently.
Niu, Yuanling, Wang, Yue, Zhou, Da
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Population ecology of the blue crab Callinectes danae (Crustacea: Portunidae) in a Brazilian tropical estuary

open access: yesAnais da Academia Brasileira de Ciências, 2012
This paper aims at describing the population ecology of the swimming crab Callinectes danae Smith, 1869 in one of the most productive estuaries of Brazil, the Santa Cruz Channel.
Marina S.L.C. Araújo   +3 more
doaj   +1 more source

Meloidogyne enterolobii, a Major Threat to Tomato Production: Current Status and Future Prospects for Its Management

open access: yesFrontiers in Plant Science, 2020
The guava root-knot nematode, Meloidogyne enterolobii (Syn. M. mayaguensis), is an emerging pathogen to many crops in the world. This nematode can cause chlorosis, stunting, and reduce yields associated with the induction of many root galls on host ...
Ashley N. Philbrick   +4 more
doaj   +1 more source

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