Results 91 to 100 of about 2,505,274 (300)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

A new bird record of Oriental Darter (Suliformes: Anhingidae) in Bhutan: range expansion and plastic entanglement mortality

Journal of Threatened Taxa
The Oriental Darter Anhinga melanogaster, ranges from Pakistan to Indonesia and the Philippines. Although it occurs in adjacent India, it has not been recorded in Bhutan.
Kelzang Dorji, Khandu Subba, Pema Dorji, Kaye L. Gutiérrez, R.J. Gutiérrez   +4 more
doaj   +1 more source

The Population Decline and Extinction of Darwin’s Frogs

PLoS ONE, 2013
Darwin's frogs (Rhinoderma darwinii and R. rufum) are two species of mouth-brooding frogs from Chile and Argentina. Here, we present evidence on the extent of declines, current distribution and conservation status of Rhinoderma spp.; including information on abundance, habitat and threats to extant Darwin's frog populations.
Soto Azat, Claudio, Valenzuela Sánchez, Andrés, Collen, Ben, Rowcliffe, J. Marcus, Veloso Martínez, Alberto, Cunningham, Andrew A.   +5 more
openaire   +6 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Population Aging and Decline Will Happen Sooner Than We Think

Social Sciences
The United Nations’ 2022 World Population Prospects suggests the global population will reach 10 billion people in 2058 and will peak in 2086. Aggregated data do not account for regional and age-group realities, which draw a more pressing picture.
Jonathan R. Guillemot, Xue Zhang, Mildred E. Warner   +2 more
doaj   +1 more source

Cities, Regions and Population Decline [PDF]

, 2017
The chapter will examine some of the key demographic trends across OECD cities and regions and will discuss some of the most important challenges facing different types of places. In particular, the links between ageing and population decline will be discussed in the context of local labour markets and shifts in long-run public policy needs.
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Dynamics of the number of birds in beech-fir forests of the Caucasian State Nature Reserve (Western Caucasus) in connection with climatic factors

Nature Conservation Research: Заповедная наука
The relevance of long-term studies of biological communities is growing every year due to global climate change and anthropogenic transformations. Monitoring the numbers of common forest-dwelling bird species in Eurasia shows a decline, particularly ...
Alexander G. Perevozov
doaj   +1 more source

Age, Growth, Life History, and Fisheries of the Sand Sole, Psettichthys melanostictus [PDF]

, 2005
Sand sole, Psettichthys melanostictus, is a small but important part of the west coast groundfish fishery. It has never been assessed and there is a limited amount of biological data for the species.
McNally, Samuel V. G., Pearson, Donald E.   +1 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source