Results 61 to 70 of about 1,243,397 (260)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Population Density

This chapter will review in detail the behavior of the population density in Mexico from 1990 to 2020. The Time Series Graph of this factor will be decom- ´ posed into the Trend T(t), Seasonal S(t), Cyclical C(t), and Irregular I(t) components. From the graphical results, we will analyze and obtain will get a method to calculate the population density ...
  +4 more sources

Effects of DNA Methylation of HPA-Axis Genes of F1 Juvenile Induced by Maternal Density Stress on Behavior and Immune Traits in Root Voles (Microtus oeconomus)—A Field Experiment

Animals
The literature shows that maternal stress can influence behavior and immune function in F1. Yet, most studies on these are from the laboratory, and replicated studies on the mechanisms by which maternal stress drives individual characteristics are still ...
Shouyang Du, Guozhen Shang, Xin Tian, Zihan Liu, Yanbin Yang, Hongxing Niu, Jianghui Bian, Yan Wu, Jinyou Ma   +8 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Anthropogenic induced changes in nesting densities of the dune-specialised digger wasp Bembix rostrata (Hymenoptera: Sphecidae)

European Journal of Entomology, 2005
Data on nesting densities of Bembix rostrata, a digger wasp inhabiting dynamic coastal dunes, were used to document the detrimental effects of trampling by cattle and vacationers.
Dries BONTE
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Türkiye'de Elektrik Tüketimi ve Ekonomik Büyüme Arasındaki İlişkinin Bölgesel Analizi

Ekonomi, Politika & Finans Araştırmaları Dergisi
Elektrik tüketimi ülkelerin gelişmişlik düzeyini ölçmede önemli bir gösterge olarak kabul edilmektedir. Ekonomik büyüme, kentleşme, beşerî sermaye gibi pek çok unsur elektrik tüketimi ile ilişkilidir.
Neslihan Ursavaş, Şükrü Apaydın
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Regional Determinants of Energy Efficiency: Residential Energy Demand in Japan

Energies, 2018
Controlling the rapid growth of residential energy demand and enhancing energy efficiency are key policy issues in Japan. Thus, this study aims to estimate a residential energy demand function by conducting a stochastic frontier analysis and analyze the ...
Akihiro Otsuka
doaj   +1 more source