From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Population trends, convictions and imprisonment: Demographic divergence, dichotomy and diversity [PDF]
The links between population patterns and trends, and policy and planning for the justice system is important. The trends in the number of convictions and imprisonments by regional councils are investigated for the period 1986 to 2001. This does not just
Pool, Ian, Baxendine, Sandra
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α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
The Recent Development of Croatia's Population – Regular and Irregular Population Trends
The recent development of Croatia’s population is burdened by many phenomena, due to which we can define it as irregular. Aggression against the newly-independent Croatian state, as well as the wars in its neighbourhood, brought about mechanical ...
Ivan Lajić
doaj
Background Drought causes severe water scarcity, which might impede sanitation and hygiene practices. India is a drought-prone country and it is also striving to attain better sanitation and hygiene practices.
Sujayita Bhattacharjee +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Life expectancy and premature mortality among insured and non-insured in India, 2019–21
Background Health insurance landscape in India has undergone rapid transformation due to expansion of both centrally and state-funded health insurance schemes, most notable being the Ayushman Bharat-Pradhan Mantri Jan Arogya Yojna (AB-PMJAY).
Ankita Roy, Jyoti Das, Sanjay K Mohanty
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Rubber plantations and drug resistant malaria: a cross-sectional survey in Cambodia
Background The ongoing spread of artemisinin resistant Plasmodium falciparum malaria is a major threat to global health. In response, countries in the Greater Mekong Sub-region, including Cambodia, have declared ambitious goals to eliminate malaria ...
Rebecca Thomson +15 more
doaj +1 more source
Views from three continents : papers presented at the 1982 ICOMP International Conference on Management of Population Programmes [PDF]
Meeting: International Committee on the Management of Population Programmes, International Conference ...
Sattar, E. +1 more
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