Results 51 to 60 of about 753,387 (250)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Study characteristics of juvenile diabetes mellitus cases in bangladesh.

Journal of Family and Reproductive Health, 2014
Objective: To identify the proportion and some selected characteristics of juvenile diabetics attending BIRDEM hospital. Materials and methods: This was a cross sectional study. The study was conducted in the BIRDEM hospital.
Rezaul Karim, Nusrat Jahan Mona
doaj  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

A natural hybrid between rudd Scardinius erythrophthalmus and bream Abramis brama from Lake Akersvann, SE Norway

Fauna Norvegica, 1985
An examination of 83 cyprinid specimens collected in Lake Akersvann, SE Norway in Sept. 1984 and in June and Sept. 1985 showed these to be natural hybrids between Scardinius erythrophthalmus and Abramis brama.
Per Pethon
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Ecology and Population Structure of Two Sympatric Rodents in a Neotropical Forest of Southeastern Brazil

Life
Rodents are the most diverse group of mammals, yet the natural history of many species remains poorly understood due to their elusive behavior. In this study, we examined the population structure, home range, space use, and food selection of two ...
Ricardo Bovendorp, Gabriela Moreno, Matheus Feitosa, Alexandre Percequillo   +3 more
doaj   +1 more source

Introduction of Atlantic salmon Salmo salar L. to the river Akerselv, Oslo

Fauna Norvegica, 1986
In 1981 Carlintagged Atlantic salmon smolts from the river Imsa and river Sandvikselv stocks, and in 1984 smolts from the river Loneelv stock were released in the river Akerselv. The smolts left the river and the inner Oslofjord few weeks after release.
Lars P. Hansen
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Life history variables of resident Brown trout Salmo trutta L. in a coastal stream in northern Norway

Fauna Norvegica, 1989
This study focused on the population structure and life history of resident Brown trout in the lower parts of a coastal stream in northern Norway. An uneven age distribution was strongly evidenced by the low number of young fish.
Trygve Hesthagen
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source