Results 211 to 220 of about 7,398,608 (386)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Common genetic variation contributes significantly to the risk of developing chronic lymphocytic leukemia

Haematologica, 2013
Maria Chiara Di Bernardo, Peter Broderick, Daniel Catovsky, Richard S. Houlston   +3 more
doaj   +1 more source

The ecological niche and population history shape mosquito population genetics on a group of three Caribbean islands. [PDF]

Parasit Vectors
Helleman P, Schrama M, Trimbos KB, Braks MAH, Schaffner F, Stroo A, Wouters RM, van der Beek JG.   +7 more
europepmc   +1 more source

Population genetics in the american tropics. VIII. The courtship isolation within Drosophila paulistorum incipient “species” [PDF]

, 1973
H. F. Hoenigsberg, L. E. Castro, G. R. de Sanabria   +2 more
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

The population genetics of convergent adaptation in maize and teosinte is not locally restricted. [PDF]

Elife
Tittes S, Lorant A, McGinty SP, Holland JB, de Jesus Sánchez-González J, Seetharam A, Tenaillon M, Ross-Ibarra J.   +7 more
europepmc   +1 more source

Some aspects of medical genetics in island populations. [PDF]

, 1971
C. A. Clarke
openalex   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Shotgun sequencing of airborne eDNA achieves rapid assessment of whole biomes, population genetics and genomic variation. [PDF]

Nat Ecol Evol
Nousias O, McCauley M, Stammnitz MR, Farrell JA, Koda SA, Summers V, Eastman CB, Duffy FG, Duffy IJ, Whilde J, Duffy DJ.   +10 more
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source