Results 71 to 80 of about 7,466,882 (388)

Landscape genetics and gene flow in the banana pathogenic fungus Mycosphaerella fijiensis [PDF]

, 2007
Among the different evolutionary forces driving population genetics, gene flow related to dispersal plays a major role in local adaptation processes. However very few studies on plant pathogenic fungi focussed on deciphering gene flow patterns at the ...
Carlier, Jean, Cogneau-Perineau, Sonia, De Lapeyre de Bellaire, Luc, Halkett, Fabien, Pignolet, Luc, Ravigné, Virginie, Rieux, Adrien, Zapater, Marie-Françoise   +7 more
core  

Unraveling the Complexity of the Ne/Nc Ratio for Conservation of Large and Widespread Pelagic Fish Species: Current Status and Challenges

Evolutionary Applications
Estimating and understanding the ratio between effective population size (Ne) and census population size (Nc) are pivotal in the conservation of large marine pelagic fish species, including bony fish such as tunas and cartilaginous fish such as sharks ...
Chrystelle Delord, Sophie Arnaud‐Haond, Agostino Leone, Jonathan Rolland, Natacha Nikolic   +4 more
doaj   +1 more source

The population genetics of evolutionary rescue. [PDF]

PLoS Genetics, 2014
Evolutionary rescue occurs when a population that is threatened with extinction by an environmental change adapts to the change sufficiently rapidly to survive. Here we extend the mathematical theory of evolutionary rescue.
H Allen Orr, Robert L Unckless
doaj   +1 more source

A review of population genetics and the prospects for crop improvement

Academia Biology, 2023
This study discusses the importance of population genetics in the context of crop improvement and its role in addressing challenges related to food security.
Godswill Ntsomboh-Ntsefong, Gabriel Mahbou Somo Toukam, Benoit Constant Likeng-Li-Ngue, Kingsley Tabi Mbi, Seyum Getachew Essubalew, Mohammad Ali Shariati, Vesna Karapetkovska Hristova, Libert Brice Tonfack, Joseph Martin Bell, Emmanuel Youmbi   +9 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Using neutral cline decay to estimate contemporary dispersal: a generic tool and its application to a major crop pathogen [PDF]

, 2013
Dispersal is a key parameter of adaptation, invasion and persistence. Yet standard population genetics inference methods hardly distinguish it from drift and many species cannot be studied by direct mark-recapture methods.
Amil, Barton, Barton, Barton, Barton, Barton, Broquet, Brown, Burt, Carlier, Chen, Daguin, Dieckmann, Endler, Fisher, Gay, Giraud, Goudet, Guillot, Guillot, Halkett, Jones, Lapeyre de Bellaire, Lebreton, Lenormand, Lenormand, Lenormand, Lenormand, Lockwood, McCartney, McDonald, Mourichon, Neu, Pennisi, Rieux, Rieux, Robert, Ronce, Rousset, Rousset, Rousset, Saccheri, Sackett, Slatkin, Storey, Turelli, Zapater   +46 more
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Imputation Estimators Partially Correct for Model Misspecification [PDF]

, 2010
Inference problems with incomplete observations often aim at estimating population properties of unobserved quantities. One simple way to accomplish this estimation is to impute the unobserved quantities of interest at the individual level and then take ...
Minin, Vladimir N., O'Brien, John D., Seregin, Arseni   +2 more
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source