Results 71 to 80 of about 1,354,958 (326)

Unraveling the Complexity of the Ne/Nc Ratio for Conservation of Large and Widespread Pelagic Fish Species: Current Status and Challenges

Evolutionary Applications
Estimating and understanding the ratio between effective population size (Ne) and census population size (Nc) are pivotal in the conservation of large marine pelagic fish species, including bony fish such as tunas and cartilaginous fish such as sharks ...
Chrystelle Delord, Sophie Arnaud‐Haond, Agostino Leone, Jonathan Rolland, Natacha Nikolic   +4 more
doaj   +1 more source

Faster model-based estimation of ancestry proportions

Peer Community Journal
Ancestry estimation from genotype data in unrelated individuals has become an essential tool in population and medical genetics to understand demographic population histories and to model or correct for population structure.
Santander, Cindy G., Refoyo Martinez, Alba, Meisner, Jonas   +2 more
doaj   +1 more source

Big Bang Nucleosynthesis, Population III, and Stellar Genetics in the Galactic Halo [PDF]

, 2001
Original article can be found at: http://www.publish.csiro.au --Copyright CSIRO --DOI : 10.1071/AS01067The diverse isotopic and elemental signatures produced in different nucle- osynthetic sites are passed on to successive generations of stars.
Ryan, Sean G.
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Exploring a Pool‐seq‐only approach for gaining population genomic insights in nonmodel species

Ecology and Evolution, 2019
Developing genomic insights is challenging in nonmodel species for which resources are often scarce and prohibitively costly. Here, we explore the potential of a recently established approach using Pool‐seq data to generate a de novo genome assembly for ...
Sara Kurland, Christopher W. Wheat, Maria de laPaz Celorio Mancera, Verena E. Kutschera, Jason Hill, Anastasia Andersson, Carl‐Johan Rubin, Leif Andersson, Nils Ryman, Linda Laikre   +9 more
doaj   +1 more source

Technologically modified genes in natural populations [PDF]

, 1993
Current theories of evolutionary and ecological genetics cannot be used for general statements on risk assessment of gene technology. In a simplifying model, the genes which are transferred from artificial populations are treated like mutations in the ...
Gabriel, Wilfried, Wöhrmann, Klaus
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The contribution of statistical physics to evolutionary biology

, 2011
Evolutionary biology shares many concepts with statistical physics: both deal with populations, whether of molecules or organisms, and both seek to simplify evolution in very many dimensions.
Ao, Baake, Baake, Bak, Barton, Barton, Barton, Barton, Barton, Barton, Bauer, Beaumont, Boltzmann, Bürger, Callen, Crow, Davis, de Vladar, Demetrius, Demetrius, Derrida, Eigen, Elena, Ewens, Ewens, Fisher, Fisher, Fisher, Fisher, Frank, Frieden, Galtier, Gavrilets, Geyer, Haldane, Haldane, Hallatschek, Hallatschek, Hallatschek, Hamilton, Harold P. de Vladar, Hastings, Hermisson, Iwasa, Judson, Kauffman, Kimura, Kimura, Kimura, Kimura, Kimura, Kolmogorov, Kolmogorov, Kolmogorov, Korolev, Lande, Lande, Leibler, Livnat, Luria, Lynch, Mackay, Maynard-Smith, Maynard-Smith, Metropolis, Mustonen, Neher, Nicholas H. Barton, Peck, Peck, Penna, Price, Prügel-Bennett, Ralph, Rattray, Rouhani, Rouzine, Rouzine, Schrödinger, Sella, Shannon, Sneppen, Szymura, Taylor, Timofeéff-Ressovsky, Watkins, Wilke, Worden, Wright, Wright, Wright, Wright   +91 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database

Nature Communications
Incomplete penetrance, or absence of disease phenotype in an individual with a disease-associated variant, is a major challenge in variant interpretation.
Sanna Gudmundsson, Moriel Singer-Berk, Sarah L. Stenton, Julia K. Goodrich, Michael W. Wilson, Jonah Einson, Nicholas A. Watts, Genome Aggregation Database Consortium, Tuuli Lappalainen, Heidi L. Rehm, Daniel G. MacArthur, Anne O’Donnell-Luria   +11 more
doaj   +1 more source