Results 201 to 210 of about 661,661 (299)

Structure Formation in Butterfly Scales: Interplay of Genetic Control, Mechanical Instabilities, and Dynamic Material Properties

Advanced Functional Materials, EarlyView.
Butterfly wing scales are intricate cuticular functional nanosctructures. This perspective suggests that spatially varying material properties, cytoskeletal constraints, and growth‐driven mechanical instabilities shape the resulting nanoscale architectures created from single cells.
Anupama Prakash, Victoria Lloyd, Yi Yang, Anna‐Lee Jessop, Anthony McDougal, Primož Pirih, Guillaume Duclos, Andrew Parnell, Mathias Kolle, Nicola J. Nadeau, Bodo D. Wilts   +10 more
wiley   +1 more source

Sequencing Ultraconserved Elements (UCEs) for Marine Population Genomics: A Proof-of-Concept Using a Deep-Sea Mussel Species. [PDF]

Evol Appl
Li YX, Xu T, Perez M, Chen C, Watanabe HK, Ip JC, Qiu JW.   +6 more
europepmc   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Population Genomics and the Environmental Drivers of Population Structure in a Cosmopolitan Marine Predator, Tursiops truncatus. [PDF]

Mol Ecol
Moore DM, Moura AE, Natoli A, Papale E, Cunningham EG, Silva MA, Genov T, Gaspari S, Buscaino G, Berggren P, Gröcke DR, Hoelzel AR.   +11 more
europepmc   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

Natural Selection in Transcription Factor-DNA Interaction Motifs: A Comparative and Population Genomics Perspective. [PDF]

Genome Biol Evol
Joshi M, Duchen P, Kapopoulou A, Laurent S.   +3 more
europepmc   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Population genomics and molecular epidemiology of wheat powdery mildew in Europe. [PDF]

PLoS Biol
Jigisha J, Ly J, Minadakis N, Freund F, Kunz L, Piechota U, Akin B, Balmas V, Ben-David R, Bencze S, Bourras S, Bozzoli M, Cotuna O, Couleaud G, Cséplő M, Czembor P, Desiderio F, Dörnte J, Dreiseitl A, Feechan A, Gadaleta A, Gauthier K, Giancaspro A, Giove SL, Handley-Cornillet A, Hubbard A, Karaoglanidis G, Kildea S, Koc E, Liatukas Ž, Lopes MS, Mascher F, McCabe C, Miedaner T, Martínez-Moreno F, Nellist CF, Okoń S, Praz C, Sánchez-Martín J, Sărăţeanu V, Schulz P, Schwartz N, Seghetta D, Martel IS, Švarta A, Testempasis S, Villegas D, Widrig V, Menardo F.   +48 more
europepmc   +2 more sources

Harnessing Population Genomics, Gut Microbiota, and Environmental DNA Surveillance for the Conservation of Chinese Spotted Seals in a Changing World. [PDF]

Ecol Evol
Li S, Li W, Zhang X, Zhou H, Zhan J.
europepmc   +1 more source