Results 151 to 160 of about 14,701,690 (366)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

TO THE WAVE NATURE OF ECONOMIC CYCLES [PDF]

open access: yesRevista Romana de Economie, 2008
The question of economic cycles’ origin is still one of the most actual problems. In inorganic nature the wave process appears as a form of system’s existence and as reaction of environment against outside disturbance.
Dmitry CHISTILIN
doaj  

Analysis of Discrete Stochastic Population Models with Normal Distribution [PDF]

open access: yesarXiv
This paper analyzes a stochastic logistic difference equation under the assumption that the population distribution follows a normal distribution. Our focus is on the mathematical relationship between the average growth rate and a newly introduced concept, the uniform structural growth rate, which captures how growth is influenced by the internal ...
arxiv  

Hyperbolic Growth of the World Population in the Past 12,000 Years [PDF]

open access: yesarXiv, 2015
Data describing the growth of the world population in the past 12,000 years are analysed. It is shown that, if unchecked, population does not increase exponentially but hyperbolically. This analysis reveals three approximately-determined episodes of hyperbolic growth: 10,000-500 BC, AD 500-1200 and AD 1400-1950, representing a total of about 89% of the
arxiv  

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

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