Results 61 to 70 of about 1,587,313 (317)

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Acute toxity and sublethal effects of pymetrozine on the whitefly parasitoid Encarsia formosa Gahan [PDF]

Pesticidi i Fitomedicina, 2020
Sublethal effects of a pymetrozine-based product (commercial product Chess 50 WP) on life history traits and population growth of one commercialized strain ("Dutch" strain) and two local populations (Bujanovac and Negotin) of the whitefly parasitoid ...
Drobnjaković Tanja, Marčić Dejan
doaj  

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

A Psychological Analysis of Iranian Infertile Couples' Attitudes Toward Gestational Surrogacy: A Cross‐Sectional Study

Health Science Reports
Background and Aims In the last two decades, assisted reproductive technologies (ARTs), such as surrogacy, have helped couples address infertility. However, the use of these techniques can present moral, social, and psychological challenges for both the ...
Masoumeh Esmaeilivand, Arezoo Haseli, Alirez Karampour, Alireza Khatony, Shahab Rezaeian, Amirhossein Naghibzadeh, Mohammad Mehdi Mohammadi   +6 more
doaj   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Association of hypertriglyceridemic-waist phenotype with liver enzymes and cardiometabolic risk factors in adolescents: the CASPIAN-III study

Jornal de Pediatria, 2016
Objective: This study aims to investigate the role of metabolic syndrome (MetS) and the hypertriglyceridemic-waist (HW) phenotype in determining cardiometabolic risk factors and elevated liver enzymes in a national sample of Iranian pediatric population.
Roya Kelishadi, Fahimeh Jamshidi, Mostafa Qorbani, Mohammad Esmaeil Motlagh, Ramin Heshmat, Gelayol Ardalan, Silva Hovsepian   +6 more
doaj  

Estimating population attributable risk fraction of determinants of pediatric obesity

BMC Public Health
Objectives Childhood obesity imposes a remarkable socio-economic and health-related burden, with an increasing worldwide trend. We aimed to assess the relationship between modifiable factors and obesity in Iranian children and adolescents along with to ...
Maryam Yazdi, Ibrahim Abdollahpour, Mostafa Qorbani, Saba Karimi, Mohammad Esmail Motlagh, Majid Khademian, Roya Kelishadi   +6 more
doaj   +1 more source

Reproduction and survival of Muscina stabulans under laboratory conditions Reprodução e sobrevivência de Muscina stabulans em condições de laboratório

Ciência Rural, 2010
This is the first published report concerning reproduction and survival using life table analyses of fertility and survival for Muscina stabulans maintained under laboratory conditions with artificial diets.
Rodrigo Ferreira Krüger, Paulo Bretanha Ribeiro, Simone Giehl Erthal, Og DeSouza   +3 more
doaj   +1 more source

POPULATION GROWTH AND INDUSTRIALIZATION [PDF]

Economic Inquiry, 2008
The role of population growth in the process of industrialization is studied in a general equilibrium model. It provides a formal presentation of Rostow’s insight of the role of a leading sector in industrialization. Population growth may lead to a shortage of food and a breakdown of the industrialization process. However, population growth may benefit
openaire   +2 more sources