Results 181 to 190 of about 373,456 (271)

The second survey of the Saudi Acute Myocardial Infarction Registry Program: Main results and temporal changes in care (STARS-2 program). [PDF]

PLoS One
AlSaleh A, AlSaif SM, Alhadramy O, Alshehri M, Al Faraidy K, Almutairi F, Kinsara AJ, Al-Murayeh M, Ghabashi AE, Alasnag M, Hussein GA, Askar TM, Haider KH, Alharbi IA, Almokhlef A, Sayed BA, Almasswary A, Ul-Sabah Z, Kazim H, Albareda HA, Aldossari MA, Albawardi R, Alali R, Abdulhabeeb IAM, Ibrahim SM, Alasmari S, Almoghairi AM, Khoja AY, Hussain N, Aminu BS, Serafi A, Eltayeb AO, BuSaleh AH, Alsabatien B, Hamza MK, Alsharkawy R, Awwad AA, Mohamed MA, Al Habeeb MA, Shujauddin S, Ya'u JA, Attia NM, Kholaif N, Bin Ghouth NM, Youssef MKI, Qutub MA, Lawand SR, Alkutshan R, Ahmed E, Basardah A, Alhaj WI, Altaradi H, Ali M, Alqarawi W, Alhabib KF, STARS-2 Investigators.   +55 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Epigenetic alterations in rotator cuff tendinopathy and degenerative cuff tears: a systematic review. [PDF]

JSES Rev Rep Tech
Hatzinger BM, Lind DRG, Felan NA, Rothrauff BB, Dornan GJ, Huard J, Millett PJ.   +6 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Association of HLA class I allele and tuberculosis susceptibility: a systematic review and meta-analysis. [PDF]

Sci Rep
Kumari N, Kumar R, Patro IK, Das A.
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Hyperbilirubinemia as a Marker for Complicated Acute Appendicitis: A Systematic Review. [PDF]

Cureus
Czyszczon A, Maczkowski B, Tkaczyk A, Drozdz M, Boral W, Mikler S, Mandyna M, Przelaskowska A, Pulinski J.   +8 more
europepmc   +1 more source

The Structure of Population II Stars.

The Astrophysical Journal, 1960
openaire   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The emergence of globular clusters and globular-cluster-like dwarfs. [PDF]

Nature
Taylor ED, Read JI, Orkney MDA, Kim SY, Pontzen A, Agertz O, Rey MP, Andersson EP, Collins MLM, Yates RM.   +9 more
europepmc   +1 more source