Association Between <i>ACE</i> (I/D) Polymorphism and Essential Hypertension (EH): An Updated Systematic Review and Meta-Analysis. [PDF]
Smallwood A +5 more
europepmc +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Stereotactic ablative radiotherapy versus video-assisted lobectomy for operable stage I non-small-cell lung cancer: study protocol for an emulated target trial. [PDF]
Bedir A +8 more
europepmc +1 more source
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
The role of vitamin K in the prognosis of patients with hepatocellular carcinoma: a systematic review and meta-analysis. [PDF]
Guo L +5 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
The emergence of globular clusters and globular-cluster-like dwarfs. [PDF]
Taylor ED +9 more
europepmc +1 more source
Models for Lower Main-Sequence Population II Stars.
openaire +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Association of HLA class I allele and tuberculosis susceptibility: a systematic review and meta-analysis. [PDF]
Kumari N, Kumar R, Patro IK, Das A.
europepmc +1 more source

