Results 151 to 160 of about 201,594 (302)
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Low-mass Population III Star Formation due to the HD Cooling Induced by Weak Lyman–Werner Radiation
The Astrophysical JournalLyman–Werner (LW) radiation photodissociating molecular hydrogen (H _2 ) influences the thermal and dynamical evolution of the Population III (Pop III) star-forming gas cloud.
Sho Nishijima +2 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
AEOS: Star-by-star Cosmological Simulations of Early Chemical Enrichment and Galaxy Formation
The Astrophysical JournalThe A eos project introduces a series of high-resolution cosmological simulations that model star-by-star chemical enrichment and galaxy formation in the early Universe, achieving 1 pc resolution.
Kaley Brauer +9 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Astrophysical JournalHigh-redshift gamma-ray bursts (GRBs), putative counterparts of massive, low-metallicity population III (Pop III) stars, are a promising probe of the first stars.
Jun-Jie Wei, Qing-Bo Ma, Xue-Feng Wu
doaj +1 more source
Eruptive mass loss in very massive stars and Population III stars [PDF]
, 2009 12 pages, 4 figs. To appear in proceedings of STScI May Symposium 2006, "Massive Stars: From Pop III and GRBs to the Milky Way".
openaire +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source