Results 91 to 100 of about 7,543,790 (273)
Mean-field approximation of stochastic population processes in games [PDF]
We here establish an upper bound on the probability for deviations of a Markov population process from its mean-field approximation.
Jörgen Weibull, Michel Benaïm
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Composite Estimators for the Population Mean Under Ranked Set Sampling
MathematicsRanked Set Sampling (RSS) is an effective sampling technique, particularly when precise measurement of the study variable is costly or time-consuming, but ranking the units is relatively easy.
Sayed A. Mostafa +2 more
doaj +1 more source
Migration as a means of population control [PDF]
Population Studies, 1971 Abstract The more crowded West Indian islands lose citizens each year through emigration, and they are small enough for an appreciable relief of population pressure to be thereby afforded. Each year some of the inhabitants of Java move to Sumatra and elsewhere under official sponsorship, part of the rationale for the policy being the relief of ...
openaire +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Optimizing Finite Population Mean Estimation Using Simulation and Empirical Data
MathematicsTwo-phase sampling is an effective sampling approach that is useful in sample surveys when prior auxiliary information is not available. When two variables have an association, the ranks of the auxiliary variable are proportional to the study variable ...
Abdulaziz S. Alghamdi +1 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Alexandria Engineering JournalThis paper proposes a new family of estimators for population mean with a non-response using a simple random sampling. It specifically applies this method to estimate the mean in Turkey’s Education sector data sets, accounting for non-response. The study
Fatimah A. Almulhim +6 more
doaj +1 more source