Results 81 to 90 of about 5,085,854 (283)
New Zealand regions, 1986-2001: Population dynamics [PDF]
New Zealand regions have markedly different population dynamics. Population change in a region is driven by three different factors: fertility, mortality and migration.
Lindop, J. +3 more
core
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
In the Arcachon Basin, subject to coastal flooding, social vulnerability is increasing, in parallel with the very high population growth of this part of the French Atlantic coast.
Lydie Goeldner-Gianella +2 more
doaj +1 more source
Evolution of Cooperation in Spatially Structured Populations
Using a spatial lattice model of the Iterated Prisoner's Dilemma we studied the evolution of cooperation within the strategy space of all stochastic strategies with a memory of one round. Comparing the spatial model with a randomly mixed model showed that (1) there is more cooperative behaviour in a spatially structured population, (2) PAVLOV and ...
Brauchli K, Killingback T, Doebeli M
openaire +3 more sources
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
The spatial distribution of population is closely related to land use and land cover (LULC) patterns on both regional and global scales. Population can be redistributed onto geo-referenced square grids according to this relation.
Xiaohuan Yang +4 more
doaj +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Optimal population policy [PDF]
For more about the East-West Center, see http://www.eastwestcenter.org/This paper investigates the notion of optimality in population policy through the use of simple analytical and numerical examples.
Arthur, W. Brian +2 more
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Genetic hitchhiking in spatially extended populations
When a mutation with selective advantage s spreads through a panmictic population, it may cause two lineages at a linked locus to coalesce; the probability of coalescence is exp(-2rT), where T∼log(2Ns)/s is the time to fixation, N is the number of haploid individuals, and r is the recombination rate. Population structure delays fixation, and so weakens
Barton +4 more
openaire +3 more sources

