Results 131 to 140 of about 7,806,372 (301)

Macroscopic quantum self-trapping and atomic tunneling in two-species Bose-Einstein condensates

, 2000
We present a new theoretical treatment of macroscopic quantum self-trapping (MQST) and quantum coherent atomic tunneling in a zero-temperature two-species Bose-Einstein condensate system in the presence of the nonlinear self-interaction of each species ...
Kuang, Le-Man, Ouyang, Zhong-Wen
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Single-artificial-atom lasing using a voltage-biased superconducting charge qubit

, 2009
We consider a system composed of a single artificial atom coupled to a cavity mode. The artificial atom is biased such that the most dominant relaxation process in the system takes the atom from its ground state to its excited state, thus ensuring ...
A M Zagoskin, Franco Nori, Gardiner C W, Helmer F Mariantoni M Solano E Marquard F, J R Johansson, Meyer G M, Milonni P W, S Ashhab, Scully M O, Wendin G   +9 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Retention in Continuous Care and Sustained Viral Suppression

Journal of the International Association of Providers of AIDS Care, 2017
Objectives: To examine the relationship between retention in continuous care and sustained viral suppression. Methods: The authors retrospectively followed 653 persons who were virally suppressed and seeking care at an infectious disease clinic in ...
Timothy N. Crawford PhD, MPH, Alice Thornton MD   +1 more
doaj   +1 more source

Population suppression of Ceratitis capitata (Wiedemann) on table grapes using toxic baits.

Anais da Academia Brasileira de Ciências, 2018
To provide alternatives to the use of spraying synthetic insecticides in C. capitata management, was evaluated the effect of "attract and kill" toxic baits on population suppression of C. capitata in three commercial areas producing table grapes.
C. A. Baronio, D. Bernardi, B. A. Paranhos, F. Garcia, M. Botton   +4 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Inherited Sterility in Tuta absoluta (Lepidoptera: Gelechiidae): Pest Population Suppression and Potential for Combined Use with a Generalist Predator

Florida Entomologist, 2016
Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) is one of the most devastating pests of tomato. We studied whether partially sterile T. absoluta males and fully sterile females were capable of suppressing wild populations of this moth in semi ...
C. Cagnotti, A. Andorno, C. M. Hernández, L. Paladino, E. Botto, S. López   +5 more
semanticscholar   +1 more source