Results 181 to 190 of about 7,572,211 (397)

HEALTH VALUE IN FOOD SAFETY SURVEILLANCE INITIATIVES [PDF]

open access: yes
Recognizing the increasing concern about the potential health effects of genetically modified foods, this research provides a framework for economic value of monitoring genetically modified food for their potential long-term human health effects. This is
Amanor-Boadu, Vincent   +2 more
core   +1 more source

USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity

open access: yesAdvanced Science, EarlyView.
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang   +9 more
wiley   +1 more source

Population‐Based Surveillance and a Case‐Control Study of Risk Factors for Endemic Lymphocutaneous Sporotrichosis in Peru [PDF]

open access: bronze, 2003
G. Marshall Lyon   +9 more
openalex   +1 more source

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun   +14 more
wiley   +1 more source

Mortality transition over a quarter century in rural South Africa: findings from population surveillance in Agincourt 1993-2018. [PDF]

open access: yesGlob Health Action, 2021
Kabudula CW   +8 more
europepmc   +1 more source

ALLOCATING BIOSECURITY RESOURCES IN SPACE AND TIME [PDF]

open access: yes
Invasive species can cause significant damage to natural environments, agricultural systems, human populations and the economy as a whole. Biological invasions are complex dynamic systems which are inherently uncertain and their control involves ...
Cacho, Oscar J., Hester, Susan M.
core   +1 more source

Nanosensitizer for Cancer Radioimmunotherapy via Anti‐IL‐35 Blockade Boosted Innate Immunity Activation

open access: yesAdvanced Science, EarlyView.
Zheng et al. designed a tumor microenvironment (TME)‐responsive nanosystem, HmBMH@MSA‐2. It targets tumors, releases MSA‐2 and Mn ions in high glutathione (GSH) conditions, achieving STING agonist delivery and MRI. The nanosystem promotes chemodynamic therapy (CDT), achieves radiosensitization, and activates the cGAS‐STING pathway.
Yinfei Zheng   +11 more
wiley   +1 more source

COVID RADAR app: Description and validation of population surveillance of symptoms and behavior in relation to COVID-19. [PDF]

open access: yesPLoS One, 2021
van Dijk WJ   +12 more
europepmc   +1 more source

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