Results 111 to 120 of about 2,135,400 (251)

Rising Poverty in the Midst of Plenty: The Case of Working-Age People with Disabilities over the Business Cycles of the 1980s and 1990s. Policy Brief [PDF]

, 2005
“When you cannot measure, your knowledge is meager and unsatisfactory”—Lord Kelvin. (Chiseled on the archway of the University of Chicago Social Sciences Building).
Burkhauser, Richard V., Houtenville, Andrew J., Rovba , Ludmila   +2 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Fish fauna of the Brahmaputra River, Bangladesh: richness, threats and conservation needs

Journal of Fisheries, 2015
The Brahmaputra River is one of the largest rivers in the world as well as in Bangladesh. The present study was carried out for a period of one year from January to December 2013 with a view to assessing the availability of fishes in the river with ...
Shams Muhammad Galib
doaj  

One‐stage spatial mark–resight analysis reveals an increasing grizzly bear population with declining density near roads

Ecosphere
Wildlife ecologists throughout the world strive to monitor trends in population abundance to help manage wildlife populations and conserve species at risk.
Jesse Whittington, Mark Hebblewhite, Connor Meyer, Barb Johnston, Anne Forshner, Bryan J. Macbeth, Anthony L. Einfeldt, Seth G. Cherry   +7 more
doaj   +1 more source

Population growth and endogenous technological change: Australian economic growth in the long run [PDF]

The Australian growth experience appears to be a three-act phenomenon, with higher per capita income and living standards before 1890 and after 1940, disconnected by a 50-year period of no trend improvement in between.
Banerjee, Rajabrata
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

The Breeding colonies, population growth and breeding success of the Dalmatian pelican Pelecanus crispus in Greece: a country-wide perspective, 1967-2021

European Journal of Ecology
Greece holds the third larger breeding population of Dalmatian Pelican in the world. We present data about the establishment and growth, breeding performance and conservation status for all six colonies of the species in Greece for 40 years.
Giorgos Catsadorakis, Olga Alexandrou, Dionyssia Hatzilacou, Ioannis Kasvikis, Maria Katsikatsou, Spyros Konstas, Myrsini Malakou, Dimitrios Michalakis, Theodoros Naziridis, Haris Nikolaou, Nikolaos Noulas, Danae Portolou, Yiannis Roussopoulos, Ioannis Vergos, Alain Crivelli   +14 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source