Results 1 to 10 of about 205,786 (267)
Epigenetic Drift and the Generational Limit of Serial Somatic Cell Nuclear Transfer in Pigs [PDF]
AnimalsSomatic cell nuclear transfer (SCNT) in pigs has been a widely used technique for producing gene-edited pigs for biomedical research, yet its wide-spread application through serial cloning remains markedly limited.
Na Cheng +6 more
doaj +2 more sources
Life, 2021 The base editing 3 (BE3) system, a single-base gene editing technology developed using CRISPR/Cas9n, has a broad range of applications for human disease model construction and gene therapy, as it is highly efficient, accurate, and non-destructive.
Honghui Li +13 more
doaj +1 more source
Construction of PIK3C3 Transgenic Pig and Its Pathogenesis of Liver Damage
Life, 2022 As a member of the PIKs family, PIK3C3 participates in autophagy and plays a central role in liver function. Several studies demonstrated that the complete suppression of PIK3C3 in mammals can cause hepatomegaly and hepatosteatosis. However, the function
Jing Wang +19 more
doaj +1 more source
Current Issues in Molecular Biology, 2019 Porcine parvovirus (PPV) is considered the main cause of reproductive disorders in pigs, which are summarized under the acronym SMEDI (stillbirth, mummification, embryonic death, and infertility). In this review the biology of the virus and its structure, pathogenic potential and strain variation, as well as the disease induced by the virus, are ...
André Felipe, Streck, Uwe, Truyen
openaire +2 more sources
Small Ruminant Farming in Tribal Areas of Dera Ghazi Khan, Punjab, Pakistan
Veterinary Sciences, 2022 Provincially Administered Tribal Areas (PATA) of Punjab-Pakistan are comprised of hilly mountains with small ruminants as a sole source of income. In this study, farming practices, productivity, health and the economic value of sheep were evaluated in ...
Muhammad Ameen Jamal +12 more
doaj +1 more source
Optimized real-time fluorescence PCR assay for the detection of porcine Circovirus type 3 (PCV3)
BMC Veterinary Research, 2020 Background Porcine circovirus type 3 (PCV3) has been an emerging porcine virus spread around the world. The conserved DNA sequence of PCV3 enabled good performance in molecular biological assays.
Lin Yuan +9 more
doaj +1 more source
Detection and Characterization of Porcine Endogenous Retrovirus in Porcine Plasma and Porcine Factor VIII [PDF]
Journal of Virology, 2001 ABSTRACT The pig genome contains porcine endogenous retroviruses (PERVs) capable of infecting human cells. Detection of infectious retrovirus in porcine peripheral blood mononuclear cells and endothelial cells suggested to us that pig plasma is likely to contain PERV.
D M, Takefman +4 more
openaire +2 more sources
Role of Porcine Aminopeptidase N and Sialic Acids in Porcine Coronavirus Infections in Primary Porcine Enterocytes [PDF]
Viruses, 2020 Porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV) have been reported to use aminopeptidase N (APN) as a cellular receptor. Recently, the role of APN as a receptor for PEDV has been questioned. In our study, the role of APN in PEDV and TGEV infections was studied in primary porcine enterocytes.
Tingting Cui +4 more
openaire +5 more sources
Contribution of porcine aminopeptidase N to porcine deltacoronavirus infection [PDF]
Emerging Microbes & Infections, 2018 Porcine deltacoronavirus (PDCoV), a member of genus Deltacoronavirus, is an emerging swine enteropathogenic coronavirus (CoV). Although outstanding efforts have led to the identification of Alphacoronavirus and Betacoronavirus receptors, the receptor for Deltacoronavirus is unclear.
Xinyu Zhu +9 more
openaire +2 more sources
Frontiers in Microbiology, 2020 Porcine reproductive and respiratory syndrome (PRRS) is one of the most devastating diseases of the global swine industry. The causative agent porcine reproductive and respiratory syndrome virus (PRRSV) was first isolated in China in 1996 and has evolved
Yifeng Jiang +10 more
doaj +1 more source