Results 101 to 110 of about 162,784 (180)

Construction of prokaryotic system for expression of porcine circovirus type 2 ORF-2 gene fragment

Ветеринария сегодня
Porcine circovirus-associated diseases (PCVDs) are among the most significant challenges for pig farming in developed countries. Porcine circovirus type 2 (PCV-2) is considered the main etiological agent of postweaning multisystemic wasting syndrome in ...
A. G. Galeeva, A. R. Akhunova, K. V. Usoltsev, N. I. Khammadov, M. A. Efimova   +4 more
doaj   +1 more source

Porcine circovirus 3 (PCV-3) infection and association with disease in swine

, 2021
Porcine circovirus 3 (PCV-3) has been identified in pigs suffering from different disease conditions, as well as in healthy animals. However, the mere detection of the virus does not imply disease causality. Moreover, in most studies, a healthy control group was not included, complicating the interpretation of the potential implication of the virus in ...
openaire   +2 more sources

Investigating Porcine Circovirus Type 2 Viral Protein 3 Multimerization Capabilities

, 2013
Porcine Circovirus Type 2 (PCV-2) is a single-stranded non-enveloped DNA virus belonging to the Circoviridae family that produces a novel viral protein, Viral Protein 3 (VP3) that is suspected of selectively killing transformed human cancer cells via an ...
Teceno, Nicholas J
core   +3 more sources

3D models of proteins and conservative G-quadruplexes in the genome of porcine circovirus

Біофізичний вісник
Background: Non-canonical structures formed in nucleic acid molecules, which include, in particular, multihelical connections 3WJs (three-way junctions), quadruplexes (G4s), are regulatory elements that affect the functioning of the genome.
O. Yu. Limanskaya, O. V. Biloivan, O. K. Balak, A. P. Limanskii   +3 more
doaj   +1 more source

Porcine circovirus 3 (PCV-3) variability

The continuous discovery of new viruses during the last decades has increased the need for new classification approaches and rules. Currently, the International Committee on Taxonomy of Viruses classifies viruses up to the species level. However, because of the higher variability of most of these infectious agents, a below-species categorization is ...
Franzo, Giovanni||, Segalés Coma, Joaquim||   +1 more
openaire   +1 more source

Genotyping Porcine Circovirus 3 (PCV-3) Nowadays

The discovery of a globally distributed porcine circovirus (Porcine circovirus 3 ; PCV-3) has led to intense research activity and the production of a large amount of molecular data. Different research groups have proposed several, not always concordant, genotypes for this virus.
Franzo, Giovanni||, Delwart, Eric, Fux, Robert, Hause, Ben, Su, Shuo, Zhou, JiYong, Segalés Coma, Joaquim||   +6 more
openaire   +1 more source

Current Knowledge on Porcine circovirus 3 (PCV-3)

Porcine circovirus 3 (PCV-3) is a recently described virus belonging to the family Circoviridae. It represents the third member of genus Circovirus able to infect swine, together with PCV-1, considered non-pathogenic, and PCV-2, one of the most economically relevant viruses for the swine worldwide industry.
Klaumann, Francini, Correa-Fiz, Florencia||, Franzo, Giovanni||, Sibila Vidal, Rosa Marina||, Núñez, J. Ignacio||, Segalés Coma, Joaquim||   +5 more
openaire   +1 more source

Frequency of PCV-2 viremia in nursery piglets from a Spanish swine integration system in 2020 and 2022 considering PRRSV infection status

Porcine Health Management
Background Porcine circovirus 2 (PCV-2) poses a significant economic threat for the swine industry, causing a range of diseases collectively referred to as porcine circovirus diseases (PCVDs).
Mònica Sagrera, Laura Garza-Moreno, Marina Sibila, Salvador Oliver-Ferrando, Sonia Cárceles, Carlos Casanovas, Patricia Prieto, Alberto García-Flores, David Espigares, Joaquim Segalés   +9 more
doaj   +1 more source

Further evidence of the host plasticity of porcine circovirus-2: detection of the virus in domestic dogs in Namibia

BMC Veterinary Research
Porcine circovirus 2 (PCV-2) is a major pathogen of swine, causing significant production losses in the pig industry worldwide. Several studies have detected the virus in different species, both in asymptomatic and diseased subjects, highlighting PCV-2 ...
Umberto Molini, Lourens de Villiers, Lauren M. Coetzee, Herschelle P. Green, Mari de Villiers, Siegfried Khaiseb, Giovanni Cattoli, William G. Dundon, Giovanni Franzo   +8 more
doaj   +1 more source

Circovirus Rep evades immune restriction by disrupting cGAS oligomerization and phase separation.

PLoS Pathogens
Cyclic GMP-AMP synthase (cGAS) is a key sensor of double-stranded DNA (dsDNA), initiating oligomerization and phase separation to drive immune responses against pathogens and endogenous damage.
Hongyan Yin, Zhenchao Zhao, Ye Yuan, Minjie Li, Lvye Chai, Weiyu Qu, Yan Ya, Haiwei Wang, Xin Li   +8 more
doaj   +1 more source