Comparative field efficacy of all-in-one intradermal vaccine based on an inactivated recombinant <i>Mycoplasma hyopneumoniae</i> with an embedded/integrated porcine circovirus type 2 (PCV2) capsid protein and concurrent administration with monovalent of <i>M. hyopneumoniae</i> and PCV2 intradermal vaccine. [PDF]
Suh J, Ham S, Chae C.
europepmc +1 more source
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Porcine Circovirus type 2 infected myocardial tissue transcriptome signature
Gene, 2022The goal of this study was to compare the global gene expression profile in cardiac tissues of pig infected with porcine circovirus 2 (PCV2) to that of healthy cells. Since PCV2 infection causes severe cardiovascular lesions, the myocardial tissue model was chosen for this study.
Rajib, Deb +12 more
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Kinetics of porcine circovirus type 2 replication
Archives of Virology, 2002The kinetics of porcine circovirus type 2 (PCV2) replication in PK15 cells was examined. During productive infection, viral antigens, RNA transcripts and progeny viruses all increased in a time dependent manner. Viral antigens were observed in a few cells at 18 hour postinfection (h p.i.) and cell-free progeny viruses began to appear at about 30 h p.i.
A K, Cheung, S R, Bolin
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Infection studies on human cell lines with porcine circovirus type 1 and porcine circovirus type 2
Xenotransplantation, 2004Abstract: Background: The lack of human donor organs in allotransplantation has led to a proposal for the use of porcine tissues and organs as alternative therapeutic material for humans. Besides immunological problems like graft rejection, one of the major concerns is the transmission of porcine microorganisms as viruses, bacteria and fungi to a ...
Kim, Hattermann +5 more
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Immunologic Features of Porcine Circovirus Type 2 Infection
Viral Immunology, 2002Clinical expression of porcine circovirus 2 (PCV-2) infection in swine may result in two distinct high mortality disease syndromes. In North America, postweaning multisystemic wasting syndrome (PMWS), while still sporadic in incidence, predominates. In Europe and elsewhere, both PMWS and a second syndrome, porcine dermatitis and nephropathy syndrome ...
Steven, Krakowka +6 more
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Recombination of two porcine circovirus type 2 strains
Archives of Virology, 2009Pigs can be concurrently infected with different PCV2 strains. In this study, a cell-culture-adapted PCV2 strain, originating from a PMWS-affected pig, was purified by limiting dilution. Three different strains were obtained, and one of them was a perfect mosaic of the other two, with recombination breakpoints in ORF1 and ORF2.
David J, Lefebvre +3 more
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PCV2 is globally spread pathogen involved in a number of diseases (PCVD). Commonly used vaccines against PCV2 are proved to be highly efficacious. The role of recently discovered PCV3 for pig health and interference with PCV2 remains unknown. The study performed on serum samples from seven farms vaccinated against PCV2 and four non-vaccinated showed ...
Aleksandra Woźniak +3 more
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T Lymphocyte Epitope Mapping of Porcine Circovirus Type 2
Viral Immunology, 2007Immunoreactive T lymphocyte epitopes within the ORF1, ORF2, and ORF 3 products of porcine circovirus type 2 (PCV2) were mapped. For this, overlapping linear 20-mer peptides were synthesized and tested for their ability to induce T lymphocyte proliferation in porcine peripheral blood mononuclear cells (PBMCs) isolated from experimentally PCV2-infected ...
Stevenson, L.S. +6 more
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Genetic analysis of porcine circovirus type 2 in China
Archives of Virology, 2017Porcine circovirus type 2 (PCV2) is the cause of postweaning multisystemic wasting syndrome (PMWS), which encompasses several distinct symptoms in pigs. PCV2 infection and clinical incidence of PMWS have increased in recent years, possibly due to shifts in viral populations and mutations.
Cheng-Gang, Jiang +6 more
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