Results 201 to 210 of about 78,388 (268)

Beyond a Conduit: The Evolution of Functional Biliary Stents From Active Intervention to Enabling Platforms

iNew Medicine, Volume 2, Issue 1, March 2026.
This review traces the evolution of functional biliary stents, outlining the paradigm shift from “active intervention” strategies that target stent failure to next‐generation “enabling platforms.” These platforms leverage biodegradable materials, 3D/4D printing, and smart sensors to achieve personalized, regenerative, and theranostic solutions ...
Muhan Li, Xu Liu, Xin Ye, Zhixia Dong, Xinjian Wan   +4 more
wiley   +1 more source

Bacteriophage Therapy: Current Strategies and Future Perspectives

MedComm, Volume 7, Issue 3, March 2026.
This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou, Hanyu Fu, Mengzhe Li, Zhongyu Han, Zhenchao Wu, Huahao Fan, Ning Shen, Jiajia Zheng   +7 more
wiley   +1 more source

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

MedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem, Atif Ali, Wajid Ali, Yuying Cheng, Zhibin Yan, Chaoyi Xia, Chenguang Liu, Caiyun Fu, Yiren Hu, Xi Wang   +9 more
wiley   +1 more source

Protective Effects of Fucoidan against Hydrogen Peroxide-Induced Oxidative Damage in Porcine Intestinal Epithelial Cells. [PDF]

Animals (Basel), 2019
Li Y, Zhao W, Wang L, Chen Y, Zhang H, Wang T, Yang X, Xing F, Yan J, Fang X.   +9 more
europepmc   +1 more source

Effect of quercetin and its methylated derivatives on porcine intestinal epithelial cells

, 2019
Flavonoids display various beneficial effects in the human and animal body. Their anti-inflammatory, anti-cancer, anti-bacterial properties have been shown in several studies. The above-mentioned positive effects of these compounds are often attributed to their antioxidant properties which is in close correlation to the number and position of hydroxyl ...
openaire   +1 more source

Trends in Dietary Exosome‐Like Nanoparticles: Preparation, Nutritional Functions, Bioactive Delivery Efficacy, Human Health Effects, and Future Product Development

Small Structures, Volume 7, Issue 3, March 2026.
This graphical abstract summarizes the current advances in dietary exosome‐like nanoparticles (ELNs), highlighting their biogenesis pathways (MVB‐dependent, vacuole‐mediated, and EXPO routes), molecular composition (nucleic acids, lipids, proteins, and bioactive compounds), and major preparation strategies including differential ultracentrifugation ...
Nidesha Randeni, Jinhai Luo, Min‐Hsiung Pan, Baojun Xu   +3 more
wiley   +1 more source

Enzyme‐Powered DNA Origami Nanostructures for Enhanced Mucosal Diffusion

Small Structures, Volume 7, Issue 3, March 2026.
Single‐particle tracking reveals how DNA origami navigates mucus. Bare structures show limited diffusion, while enzyme‐functionalized nanostructures exhibit enhanced mobility. Symmetrically arranged urease creates uniform pH gradients for smooth propulsion, whereas asymmetrically placed catalase drives bubble‐mediated motion.
Matteo Tollemeto, Emily Tsang, Lars J. M. M. Paffen, Lasse H. E. Thamdrup, Jan van Hest, Tania Patiño Padial, Kurt V. Gothelf, Anja Boisen   +7 more
wiley   +1 more source

The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation

Andrology, Volume 14, Issue 3, Page 747-765, March 2026.
Abstract Background The oxytocin receptor (OR) is a G‐protein‐coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunoblotting, and investigate ...
Jesús Martínez‐Hernández, Ferran Garriga, Adeel Ahmad, Lorena Padilla, Carolina Maside, Sergi Bonet, Isabel Barranco, Jordi Roca, Luis Miguel Pastor, Marc Yeste   +9 more
wiley   +1 more source

Insights Into Gut Barrier Dysfunction and Metabolic Alterations in Mycophenolate‐Induced Enteropathy

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Mycophenolic acid (MPA) is a widely used immunosuppressant whose use is often limited by gastrointestinal toxicity. Gut bacterial hydrolysis of liver‐derived MPA glucuronides increases local exposure to MPA, potentially impairing epithelial barrier function and cellular metabolism.
Clarisse Brossier, François‐Ludovic Sauvage, Christel Valencia‐Schmitt, Valérie Calco, Pascal Villa, Pierre Marquet, Roland Lawson   +6 more
wiley   +1 more source

Distribution and activity of nitrate and nitrite reductases in the microbiota of the human intestinal tract

The FEBS Journal, Volume 293, Issue 6, Page 1624-1642, March 2026.
Nitrate from food is first converted to nitrite by oral bacteria and then further processed in the intestine. The gut microbiota reduces nitrate and nitrite to ammonia or nitric oxide, preventing the formation of carcinogenic nitrosamines. Our analysis highlights Escherichia coli as a key player in this detoxification process, supported by other ...
Natalie Hager, Mélanie Elisabeth Gindt, Marcel Hövels, Jean‐Lou Christian Michel Dorne, Uwe Deppenmeier   +4 more
wiley   +1 more source