Results 211 to 220 of about 18,891 (223)

Transcriptomic and antiviral analyses of PoIFN-Delta5 against porcine enteric viruses in porcine intestinal epithelial cells

Veterinary Microbiology, 2023
The interferon-delta family was first reported in domestic pigs and belongs to the type I interferon (IFN-I) family. The enteric viruses could cause diarrhea in newborn piglets with high morbidity and mortality. We researched the function of the porcine IFN-delta (PoIFN-δ) family in the porcine intestinal epithelial cells (IPEC-J2) cells infected with ...
Xuejiao, Zhu, Baochao, Fan, Shiying, Song, Jie, Gao, Jinzhu, Zhou, Yongxiang, Zhao, Weilu, Guo, Xue, Zhang, Jiali, Qian, Mingjun, Zhu, Jizong, Li, Yunchuan, Li, Rongli, Guo, Huiying, Fan, Hailong, Dong, Xuehan, Zhang, Bin, Li   +16 more
openaire   +2 more sources

Stability of Reference Gene Expression After Porcine Sapelovirus Infection in Porcine Intestinal Epithelial Cells

Viral Immunology, 2016
Intestinal epithelial cells, which serve as the first physical barrier to protect intestinal tract from external antigens, have an important role in the local innate immunity. Screening of reference genes that have stable expression levels after viral infection in porcine intestinal epithelial cells is critical for ensuring the reliability of the ...
Yong, Huang, Yabing, Chen, Huan, Sun, Daoliang, Lan   +3 more
openaire   +2 more sources

Comparative in vitro cytotoxicity of modified deoxynivalenol on porcine intestinal epithelial cells

Food and Chemical Toxicology, 2016
The gastrointestinal tract is the first target after ingestion of the mycotoxin deoxynivalenol (DON) via feed and food. Deoxynivalenol is known to affect the proliferation and viability of animal and human intestinal epithelial cells. In addition to DON, feed and food is often co-contaminated with modified forms of DON, such as 3-acetyldeoxynivalenol ...
Nathan Broekaert, Mathias Devreese, Kristel Demeyere, Franz Berthiller, Herbert Michlmayr, Elisabeth Varga, Gerhard Adam, Evelyne Meyer, Siska Croubels   +8 more
openaire   +2 more sources

Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells

Food & Function, 2021
Kaempferol blocked diquat-induced ROS generation in IPEC-1 cells.
Yuhang Jin, Zhian Zhai, Hai Jia, Jinhua Lai, Xuemeng Si, Zhenlong Wu   +5 more
openaire   +2 more sources

Enterotoxigenic Escherichia coli (K88) induce proinflammatory responses in porcine intestinal epithelial cells

Developmental & Comparative Immunology, 2010
Infections with F4(+) enterotoxigenic Escherichia coli (ETEC) causes severe diarrhoea in piglets, resulting in morbidity and mortality. F4 fimbriae are the key virulence factors mediating the attachment of F4(+) ETEC to the intestinal epithelium. Intestinal epithelial cells (IEC) are recently being recognized as important regulators of the intestinal ...
Bert, Devriendt, Edith, Stuyven, Frank, Verdonck, Bruno M, Goddeeris, Eric, Cox   +4 more
openaire   +2 more sources

Regulation of protein turnover by l-glutamine in porcine intestinal epithelial cells

The Journal of Nutritional Biochemistry, 2012
L-Glutamine (Gln) plays an important role in sustaining the intestinal mucosal mass of humans and animals. However, the underlying mechanisms are largely unknown. This study tested the hypothesis that Gln regulates protein turnover in intestinal epithelial cells.
Pengbin, Xi, Zongyong, Jiang, Zhaolai, Dai, Xilong, Li, Kang, Yao, Chuntian, Zheng, Yingcai, Lin, Junjun, Wang, Guoyao, Wu   +8 more
openaire   +2 more sources

Arf1 promotes porcine intestinal epithelial cell proliferation via the mTORC1 signaling pathway

In Vitro Cellular & Developmental Biology - Animal
The promotion of gut health, a pervasive problem in modern animal husbandry, positively affects organismal health, productivity, and economics. Porcine intestinal epithelial cells (IPEC-J2) continuously proliferate to maintain intestinal homeostasis, including barrier, immune, and absorptive functions.
Yong-xia Fang, En-qing Lu, E. Xu, Yi-yu Zhang, Min Zhu   +4 more
openaire   +2 more sources

Integrin αvβ3 enhances replication of porcine epidemic diarrhea virus on Vero E6 and porcine intestinal epithelial cells

Veterinary Microbiology, 2019
The entry mechanism of porcine epidemic diarrhea virus (PEDV) remains unclear, especially the virus receptor. Our previous study revealed a potential correlation between integrin αvβ3 and PEDV infection. In the current study, the effect of overexpression, silencing, antibody inhibition, and co-expression with porcine aminopeptidase N (pAPN) of integrin
Chunqiu, Li, Mingjun, Su, Baishuang, Yin, Donghua, Guo, Shan, Wei, Fanzhi, Kong, Li, Feng, Rui, Wu, Dongbo, Sun   +8 more
openaire   +2 more sources

Glutamine Promotes Porcine Intestinal Epithelial Cell Proliferation through the Wnt/β-Catenin Pathway

Journal of Agricultural and Food Chemistry
Glutamine (Gln) is a critical nutrient required by neonatal mammals for intestinal growth, especially for newborn piglets. However, the mechanisms underlying the role of Gln in porcine intestinal epithelium development are not fully understood. The objective of the current study was to explore the possible signaling pathway involved in the promotion of
Yong-xia Fang, En-qing Lu, Yu-jie Cheng, E. Xu, Min Zhu, Xiang Chen   +5 more
openaire   +2 more sources

Alleviation effect of taxifolin on diquat-induced damage to porcine intestinal epithelial cells

Biochemical and Biophysical Research Communications
Oxidative stress is considered to be a major cause of numerous intestinal diseases, and taxifolin (TA) possesses a variety of pharmacological properties that promote health and prevent disease. This study intends to determine the ability of TA to alleviate oxidative stress induced by diquat (DIQ) in porcine intestinal epithelial cells (IPEC-J2 cells ...
Ke Huang, Yuting Li, Yiyu Zhang, Min Zhu
openaire   +2 more sources