Results 41 to 50 of about 18,891 (223)

Comparative Transcriptome Profiling of Human and Pig Intestinal Epithelial Cells after Porcine Deltacoronavirus Infection

Viruses, 2021
Porcine deltacoronavirus (PDCoV) is an emerging infectious disease of swine with zoonotic potential. Phylogenetic analysis suggests that PDCoV originated recently from a host-switching event between birds and mammals.
Diana Cruz-Pulido, Patricia A. Boley, Wilberforce Zachary Ouma, Moyasar A. Alhamo, Linda J. Saif, Scott P. Kenney   +5 more
doaj   +1 more source

EAAT3 promotes amino acid transport and proliferation of porcine intestinal epithelial cells

Oncotarget, 2016
Excitatory amino acid transporter 3 (EAAT3, encoded by SLC1A1) is an epithelial type high-affinity anionic amino acid transporter, and glutamate is the major oxidative fuel for intestinal epithelial cells. This study investigated the effects of EAAT3 on amino acid transport and cell proliferation through activation of the mammalian target of the ...
Ye, Jin-ling, Gao, Chun-qi, Li, Xiang-guang, Jin, Cheng-long, Wang, Dan, Shu, Gang, Wang, Wen-ce, Kong, Xiang-feng, Yao, Kang, Yan, Hui-chao, Wang, Xiu-qi   +10 more
openaire   +3 more sources

Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype. [PDF]

PLoS ONE, 2015
The human CLCA4 (chloride channel regulator, calcium-activated) modulates the intestinal phenotype of cystic fibrosis (CF) patients via an as yet unknown pathway.
Stephanie Plog, Nikolai Klymiuk, Stefanie Binder, Matthew J Van Hook, Wallace B Thoreson, Achim D Gruber, Lars Mundhenk   +6 more
doaj   +1 more source

Toll-like receptor 5-mediated IL-17C expression in intestinal epithelial cells enhances epithelial host defense against F4+ ETEC infection

Veterinary Research, 2019
Enterotoxigenic Escherichia coli (ETEC) are an important cause of post-weaning diarrhea (PWD) in piglets. The IL-17 cytokine family is well known to play important roles in the host defense against bacterial infections at the mucosa.
Yu Luo, Jia Xu, Chaoying Zhang, Chunyan Jiang, Yanfeng Ma, Haijian He, Yuan Wu, Bert Devriendt, Eric Cox, Hongbin Zhang   +9 more
doaj   +1 more source

Potential Toxicity and Mechanisms of T-2 and HT-2 Individually or in Combination on the Intestinal Barrier Function of Porcine Small Intestinal Epithelial Cells

Toxins, 2023
Under natural conditions, T-2 toxin can be easily metabolized to HT-2 toxin by deacetylation, and T-2 and HT-2 are usually co-contaminated in grain and feed at a high detected rate.
Weihua He, Jianhua Wang, Mengyi Han, Lihua Wang, Ling Li, Jiahui Zhang, Siqi Chen, Jiayi Guo, Xiaohu Zhai, Junhua Yang   +9 more
doaj   +1 more source

Effect of Fumonisin B1 on Proliferation and Apoptosis of Intestinal Porcine Epithelial Cells

Toxins, 2022
Fumonisin B1 (FB1), which is a mycotoxin produced by Fusarium moniliforme and Fusarium rotarum, has a number of toxic effects in animals. Moldy feed containing FB1 can damage the intestine. In this study, we used intestinal porcine epithelial cells (IPEC-J2) as an in vitro model to explore the effects of FB1 on cell cycle and apoptosis.
Tianjie Wang, Hongyu Lei, Lihua Zhou, Meiwen Tang, Qing Liu, Feng Long, Qing Li, Jianming Su   +7 more
openaire   +3 more sources

E. coli Nissle 1917 Affects Salmonella Adhesion to Porcine Intestinal Epithelial Cells

PLoS ONE, 2011
The probiotic Escherichia coli strain Nissle 1917 (EcN) has been shown to interfere in a human in vitro model with the invasion of several bacterial pathogens into epithelial cells, but the underlying molecular mechanisms are not known.In this study, we investigated the inhibitory effects of EcN on Salmonella Typhimurium invasion of porcine intestinal ...
Schierack, Peter, Kleta, Sylvia, Tedin, Karsten, Babila, Julius Tachu, Oswald, Sibylle, Oelschlaeger, Tobias A., Hiemann, Rico, Paetzold, Susanne, Wieler, Lothar H.   +8 more
openaire   +6 more sources

Effects of spermine on the proliferation and migration of porcine intestinal epithelial cells

Animal Biotechnology, 2021
Whether spermine promotes the repair of porcine intestinal epithelium damage through Ras-related C3 botulinum toxin substrate 1 (Rac1)/phospholipase C-γ1 (PLC-γ1) signaling remains unclear. The current study investigated the effects of spermine addition on the proliferation and migration of IPEC-J2 cells and the effects of Rac1/PLC-γ1 signaling on cell
Xiaomei Xu, Guangmang Liu, Gang Jia, Hua Zhao, Xiaoling Chen, Caimei Wu, Jing Wang   +6 more
openaire   +2 more sources

Mechanism Analysis of UCP2 During the Oxidative Stress Injury of Intestinal Porcine Epithelial Cell Line-J2

Animals
Oxidative stress poses a significant challenge in livestock production, impairing intestinal function, nutrient absorption, and overall animal performance.
Weide Su, Chuanhui Xu, Hongping Jiang, Wenjing Song, Pingwen Xiong, Jiang Chen, Gaoxiang Ai, Qiongli Song, Zhiheng Zou, Qipeng Wei, Xiaolian Chen   +10 more
doaj   +1 more source

Protects Porcine Intestinal Barrier from Deoxynivalenol via Improved Zonula Occludens-1 Expression [PDF]

Asian-Australasian Journal of Animal Sciences, 2014
Intestinal epithelial cells (IECs) forming the barrier for the first-line of protection are interconnected by tight junction (TJ) proteins. TJ alteration results in impaired barrier function, which causes potentially excessive inflammation leading to ...
Min Jeong Gu, Sun Kwang Song, Sung Moo Park, In Kyu Lee, Cheol-Heui Yun   +4 more
doaj   +1 more source